Delta variant of covid-19 study, and why it is a concern: An overview

Abstract

COVID-19 is caused by the virus SARS-CoV-2 that belongs to the Coronaviridae groups. The subgroups of the coronavirus families are α, β, γ, and δ coronavirus (the four general human coronaviruses). Representative coronaviruses consist of NL63 coronavirus (human) and porcine transmissible gastroenteritis from the Alphacoronavirus genus; mouse hepatitis coronavirus (MHV), bovine coronavirus (BCoV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV); avian infectious bronchitis virus (IBV); and porcine δ-coronavirus (PdCoV). This work exhibits, δ-coronavirus spikes are fundamentally and evolutionally more similar related to α-coronavirus spikes than to β-coronavirus or γ-coronavirus spikes due to the receptor recognition, membrane fusion phenomenon, and immune evasion behavior.