Scopus: Circulatory cytokines during the piroplasm stage of natural Theileria annulata infection in cattle
dc.contributor.author | Tümer K.Ç. | |
dc.contributor.author | Kızıl M. | |
dc.date.accessioned | 2023-04-11T22:12:51Z | |
dc.date.accessioned | 2023-04-12T00:29:10Z | |
dc.date.available | 2023-04-11T22:12:51Z | |
dc.date.available | 2023-04-12T00:29:10Z | |
dc.date.issued | 2023-01-01 | |
dc.description.abstract | The objective of the present study was to investigate the inflammatory and anti-inflammatory cytokine response from a broad perspective in cattle with natural Theileria annulata infection. Ten cattle naturally infected with T. annulata and eight healthy cattle were included in this study. A total of 11 cytokines, including tumour necrosis factor-α (TNF-α), interferon-γ (IFN-γ), interleukin (IL)-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12, IL-13, and IL-17 were evaluated in serum samples using commercially available enzyme-linked immunosorbent assay (ELISA) kits. There was no statistical significance for serum TNF-α, IL-1β, IL-5, IL-6, and IL-17 levels between the T. annulata infected and healthy cattle. In contrast, the median serum levels of IFN-γ (p =.023), IL-2 (p =.066), IL4 (p =.0016), IL-10 (p =.00087), IL-12 (p =.00018), and IL-13 (p =.023) were significantly higher in T. annulata-infected cattle than in healthy cattle. The results of the present study revealed that in the intraerythrocytic stage of tropical theileriosis, a very pronounced anti-inflammatory response occurs as well as an ongoing inflammatory process. | |
dc.identifier.doi | 10.1111/pim.12973 | |
dc.identifier.issn | 1419838 | |
dc.identifier.pubmed | 36710366 | |
dc.identifier.scopus | 2-s2.0-85147582642 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12597/3845 | |
dc.relation.ispartof | Parasite Immunology | |
dc.rights | false | |
dc.subject | anaemia | bovine | cytokine | piroplasm stage | T. annulata | tick | |
dc.title | Circulatory cytokines during the piroplasm stage of natural Theileria annulata infection in cattle | |
dc.type | Article | |
dspace.entity.type | Scopus | |
person.affiliation.name | Kastamonu University | |
person.affiliation.name | Firat Üniversitesi | |
person.identifier.orcid | 0000-0002-2861-0236 | |
person.identifier.scopus-author-id | 57205741344 | |
person.identifier.scopus-author-id | 17434694700 | |
relation.isPublicationOfScopus | 4d47199d-c450-4a7c-be27-b3645daef735 | |
relation.isPublicationOfScopus.latestForDiscovery | 4d47199d-c450-4a7c-be27-b3645daef735 |