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Effects of dietary marine sulphated polysaccharides (Algimun®) on growth performance, immune responses and disease resistance of juvenile gilthead seabream (Sparus aurata) to Photobacterium damselae subsp. piscicida

dc.contributor.authorGüroy D.
dc.contributor.authorGüroy B.
dc.contributor.authorBilen S.
dc.contributor.authorTerzi E.
dc.contributor.authorKenanoğlu O.N.
dc.contributor.authorGarcía-Suárez M.
dc.contributor.authorMarzin D.
dc.contributor.authorMantoğlu S.
dc.contributor.authorKaradal O.
dc.contributor.authorŞahin İ.
dc.contributor.authorKuşku H.
dc.date.accessioned2023-04-11T22:24:34Z
dc.date.accessioned2023-04-12T00:28:41Z
dc.date.available2023-04-11T22:24:34Z
dc.date.available2023-04-12T00:28:41Z
dc.date.issued2022-08-01
dc.description.abstractThe present study evaluated the effects of a dietary mix of marine sulphated polysaccharides, named Algimun® (AL), supplementation to gilthead seabream (Sparus aurata) juveniles in terms of growth performance, immune responses, and resistance against Photobacterium damselae subsp. piscicida. A total of 240 fish (initial mean weight of 6.00 ± 0.03 g) was randomly separated into 12 tanks (400 L, 20 fish per tank) distributed in four replicates. Fish were fed three experimental diets: a basal diet (Control), and a basal diet with two inclusion rates of Algimun® as 3 g/kg (AL0.3) and 5 g/kg (AL0.5) for 30 days before bacterial infection with P. damselae subsp. piscicida. After a 30-day feeding-period, growth performance was significantly improved in AL0.3 and AL0.5 groups compared to the control group (P < 0.05). AL0.3 and AL0.5 groups showed significantly higher lysozyme activity and myeloperoxidase activity when compared to the control group (P < 0.05). The gene expression of immune mediators (IL-1β, IL-6, IL-10, IL-18, TNF-α and COX-2) was significantly upregulated in the intestine, spleen and head kidney in AL0.3 and AL0.5 groups when compared to the control group (P < 0.05). Eight days post-challenge, the survival rate against P. damselae subsp. piscicida was numerically higher in fish within AL0.3 and AL0.5 groups compared to control (+20%). The study findings suggest that marine sulphated polysaccharides (Algimun®) could be used as an immunomodulator in gilthead seabream to support animal's health and boost resistance in case of disease outbreak.
dc.identifier.doi10.1016/j.fsi.2022.07.054
dc.identifier.issn10504648
dc.identifier.pubmed35870744
dc.identifier.scopus2-s2.0-85135725600
dc.identifier.urihttps://hdl.handle.net/20.500.12597/3721
dc.relation.ispartofFish and Shellfish Immunology
dc.rightsfalse
dc.subjectImmunomodulation | Marine fish | Marine sulphate polysaccharide | Nutrition | Seaweed
dc.titleEffects of dietary marine sulphated polysaccharides (Algimun®) on growth performance, immune responses and disease resistance of juvenile gilthead seabream (Sparus aurata) to Photobacterium damselae subsp. piscicida
dc.typeArticle
dspace.entity.typeScopus
oaire.citation.volume127
person.affiliation.nameYalova Üniversitesi
person.affiliation.nameYalova Üniversitesi
person.affiliation.nameKastamonu University
person.affiliation.nameKastamonu University
person.affiliation.nameKastamonu University
person.affiliation.nameOlmix Group
person.affiliation.nameOlmix Group
person.affiliation.nameYalova Üniversitesi
person.affiliation.nameİzmir Kâtip Çelebi Üniversitesi
person.affiliation.nameYalova Üniversitesi
person.affiliation.nameÇanakkale Onsekiz Mart Üniversitesi
person.identifier.orcid0000-0002-8254-1403
person.identifier.orcid0000-0003-2811-6497
person.identifier.orcid0000-0002-5097-6656
person.identifier.orcid0000-0002-6241-5039
person.identifier.scopus-author-id14037284300
person.identifier.scopus-author-id14037255400
person.identifier.scopus-author-id25229655300
person.identifier.scopus-author-id36451632800
person.identifier.scopus-author-id57209731467
person.identifier.scopus-author-id57837189800
person.identifier.scopus-author-id57837397800
person.identifier.scopus-author-id55043198200
person.identifier.scopus-author-id57189071594
person.identifier.scopus-author-id57209115443
person.identifier.scopus-author-id53064014500
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relation.isPublicationOfScopus.latestForDiscoverydbc7f137-deae-4a72-b3da-b390750b94f5

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