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Lymphocyte DNA damage in Turkish asphalt workers detected by the comet assay.

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dc.contributor.authorBacaksiz, Aysegul
dc.contributor.authorKayaalti, Zeliha
dc.contributor.authorSoylemez, Esma
dc.contributor.authorTutkun, Engin
dc.contributor.authorSoylemezoglu, Tulin
dc.date.accessioned2023-04-10T13:08:53Z
dc.date.accessioned2023-04-12T00:26:13Z
dc.date.available2023-04-10T13:08:53Z
dc.date.available2023-04-12T00:26:13Z
dc.date.issued2013-05-03
dc.description.abstractAsphalt has a highly complex structure and it contains several organic compounds including polycyclic aromatic hydrocarbons and heterocyclic compounds. In this study, comet assay was used to detect the DNA damage in blood lymphocytes of 30 workers exposed to asphalt fumes and 30 nonexposed controls. This is the first report on Turkish asphalt workers' investigated DNA damage using the alkaline single cell gel electrophoresis (SCGE). The DNA damage was evaluated by the percentage of DNA in the comet tail (% tail DNA) for each cell. According to our results, workers exposed to asphalt fumes had higher DNA damage than the control group (p < 0.01). The present study showed that asphalt fumes caused a significant increase in DNA damage and the comet assay is a suitable method for determining DNA damage in asphalt workers.
dc.identifier.doi10.1080/09603123.2013.773586
dc.identifier.issn1369-1619
dc.identifier.pubmed23638654
dc.identifier.urihttps://hdl.handle.net/20.500.12597/3628
dc.language.isoen
dc.relation.ispartofInternational journal of environmental health research
dc.titleLymphocyte DNA damage in Turkish asphalt workers detected by the comet assay.
dc.typeJournal Article
dc.typeResearch Support, Non-U.S. Gov't
dspace.entity.typePubmed
oaire.citation.issue1
oaire.citation.volume24
relation.isPublicationOfPubmed1d7eea8b-ef17-4075-b020-37133629fdf3
relation.isPublicationOfPubmed.latestForDiscovery1d7eea8b-ef17-4075-b020-37133629fdf3

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