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Molecular analysis of the env, LTR, and pX regions of bovine leukemia virus in dairy cattle of Türkiye

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dc.contributor.authorDuran-Yelken, S.
dc.contributor.authorAlkan, F.
dc.date.accessioned2024-02-16T05:27:44Z
dc.date.available2024-02-16T05:27:44Z
dc.date.issued2024
dc.description.abstractBovine leukemia virus is a retrovirus that causes enzootic bovine leukosis and is associated with global economic losses in the livestock industry. The aim of this study was to investigate the genotype determination of BLVs from cattle housed in 6 different farms in Türkiye and the characterization of their LTR and pX (tax, rex, R3, and G4 gene) regions. For this purpose, blood samples from 48 cattle infected with BLV were used. The phylogenetic analysis based on the env gene sequences revealed that all BLVs were clustered in genotype 1 (G1), and the sequences of the LTR (n = 48) and the pX region (n = 33) of BLVs were obtained. Also, analysis of these nucleic acid and amino acid sequences allowed assessments similar to those reported in earlier studies to be relevant to transactivation and pathogenesis. This study reports the molecular analysis of the LTR and pX region of BLVs in Türkiye for the first time.
dc.identifier.doi10.1007/s11262-024-02058-7
dc.identifier.pubmed38355991
dc.identifier.urihttps://hdl.handle.net/20.500.12597/19037
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBovine leukemia virus (BLV)
dc.subjectEnv gene
dc.subjectLTR region
dc.subjectMolecular analysis
dc.subjectpX region
dc.titleMolecular analysis of the env, LTR, and pX regions of bovine leukemia virus in dairy cattle of Türkiye
dc.typeArticle
dspace.entity.typePubmed
local.indexed.atPubMed
person.identifier.orcid0000-0003-0633-3132
person.identifier.orcid0000-0003-3854-6503

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