Pubmed:
Evaluation of subclinical retinopathy and angiopathy with OCT and OCTA in patients with systemic lupus erythematosus.

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dc.contributor.authorIşık, Mehmed Uğur
dc.contributor.authorAkmaz, Berkay
dc.contributor.authorAkay, Fahrettin
dc.contributor.authorGüven, Yusuf Ziya
dc.contributor.authorSolmaz, Dilek
dc.contributor.authorGercik, Önay
dc.contributor.authorKabadayı, Gökhan
dc.contributor.authorKurut, İdil
dc.contributor.authorAkar, Servet
dc.date.accessioned2023-04-07T00:28:34Z
dc.date.available2023-04-07T00:28:34Z
dc.date.issued2021-01-01T00:00:00Z
dc.description.abstractTo evaluate the choroidal and retinal layers with optical coherence tomography (OCT) and retinal microvascular structures with optical coherence tomography angiography (OCTA) in systemic lupus erythematosus (SLE) patients.
dc.description.abstractIn this prospective, cross-sectional and comparative study, a total of 35 SLE patients and 35 healthy control participants were included. SLE patients who were using hydroxychloroquine (HCQ) and/or immunosuppressive agents are evaluated with OCT and OCTA. SLE patients who have no HCQ maculopathy observed in OCT were included in the patient group.
dc.description.abstractMean macular thickness and ganglion cell inner plexiform layer (GC-IPL) thicknesses were thinner in the patient group. When the parameters obtained with OCTA were evaluated, vessel (VD) and perfusion density (PD) were significantly lower in the patient group. Central foveal thickness and foveal avascular zone parameters were negatively correlated. In addition, VD and PD, and GC-IPL thicknesses were positively correlated.
dc.description.abstractApplication of OCTA for the evaluation of microvasculature in SLE patients may be useful in subclinical changes.
dc.identifier.doi10.1007/s10792-020-01561-8
dc.identifier.issn1573-2630
dc.identifier.pubmed32851556
dc.identifier.urihttps://hdl.handle.net/20.500.12597/3432
dc.language.isoen
dc.relation.ispartofInternational ophthalmology
dc.subjectHydroxychloroquine
dc.subjectOptical coherence tomography
dc.subjectOptical coherence tomography angiography
dc.subjectSubclinical retinal changes
dc.subjectSystemic lupus erythematosus
dc.titleEvaluation of subclinical retinopathy and angiopathy with OCT and OCTA in patients with systemic lupus erythematosus.
dc.typeJournal Article
dspace.entity.typePubmed
oaire.citation.issue1
oaire.citation.volume41
relation.isPublicationOfPubmedef6cb8a8-155e-490d-b9d6-d811365cf135
relation.isPublicationOfPubmed.latestForDiscoveryef6cb8a8-155e-490d-b9d6-d811365cf135

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