Pubmed:
Evaluation of subclinical alterations in retinal layers and microvascular structures with OCT and OCTA in healthy young short-term smokers.

dc.contributor.authorIşik, Mehmed Uğur
dc.contributor.authorAkay, Fahrettin
dc.contributor.authorAkmaz, Berkay
dc.contributor.authorGüven, Yusuf Ziya
dc.contributor.authorŞahin, Ömer Faruk
dc.date.accessioned2023-04-06T23:42:35Z
dc.date.available2023-04-06T23:42:35Z
dc.date.issued2021-12-01T00:00:00Z
dc.description.abstractTo detect the changes that can be determined with optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) in young and short-term smokers.
dc.description.abstractIn this cross-sectional, observational, and comparative study, 45 "healthy" smokers and 45 healthy non-smoker control participants were included. Those with a smoking history between 1 year to 5 years and an average of 10-30 cigarettes per day were included in the study. OCT and OCTA measurements were made at least 60 min after smoking and at least 8 h after caffeine-containing beverages in order to end the effect of nicotine on systemic and retinal blood flow in the smoking group.
dc.description.abstractThe mean smoking period was 2.2 ± 0.13 years. Mean macular thickness(MMT), retinal nerve fiber layer(RNFL), and choroidal thickness(Cht) were significantly lower in the smoker group, while ganglion cell-inner plexiform layer(GC-IPL) thickness was higher. Vessel density(VD) values were similar between groups, while perfusion density(PD) values were significantly higher in the smoker group. There were significant correlations between MMT and outer VD, outer PD, foveal avascular zone(FAZ) perimeter and circularity index. FAZ area and central VD and PD were inversely correlated. Also, FAZ circularity index and subfoveal, nasal, and temporal ChTs were positively correlated.
dc.description.abstractDespite the short-term smoking, ischemic effects were observed in retinochoroidal and vascular structures.
dc.identifier.doi10.1016/j.pdpdt.2021.102482
dc.identifier.issn1873-1597
dc.identifier.pubmed34390879
dc.identifier.urihttps://hdl.handle.net/20.500.12597/3378
dc.language.isoen
dc.relation.ispartofPhotodiagnosis and photodynamic therapy
dc.subjectOptical coherence tomography
dc.subjectOptical coherence tomography angiography
dc.subjectSmoking
dc.titleEvaluation of subclinical alterations in retinal layers and microvascular structures with OCT and OCTA in healthy young short-term smokers.
dc.typeJournal Article
dc.typeObservational Study
dspace.entity.typePubmed
oaire.citation.volume36
relation.isPublicationOfPubmed6bd812bb-c329-468f-bb9c-6b90e5aca321
relation.isPublicationOfPubmed.latestForDiscovery6bd812bb-c329-468f-bb9c-6b90e5aca321

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