Publication: Two Flavonoids, Baicalein and Naringin, are Effective as Anti-Inflammatory and Anti-Oxidant Agents in a Rat Model of Polymicrobial Sepsis.
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In this study, our aim was to investigate the possible protective and therapeutic effects of these two flavonoids, baicalein and naringin, in 50 and 100 mg/kg doses applied both before and after cecal ligation and puncture (CLP) procedures in a polymicrobial sepsis rat model, and evaluate possible contribution of oxidative and inflammatory markers by immunological, biochemical, molecular, and histopathological methods.