Publication: 3-(4-Chloro-benzo-yl)-4-(4-chloro-phen-yl)-1-phenethyl-piperidin-4-ol
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Date
2011-06-01, 2011.01.01
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Metrikler
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Abstract
In the title compound, C26H25Cl2NO 2, the piperidine ring adopts a chair conformation with a cis configuration of the carbonyl and hy-droxy substituents. The dihedral angle between the aromatic rings of the chloro-benzene groups is 24.3 (2)°. The phenyl ring forms dihedral angles of 59.4 (3) and 44.1 (3)° with the benzene rings. In the crystal, mol-ecules are linked by inter-molecular O - H⋯N and C - H⋯O hydrogen bonds and C - H⋯π inter-actions into layers parallel to the bc plane.