Pubmed İndekslenen Yayınlar

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12597/3195

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Advanced NH3 Detection by 1D Nanostructured La:ZnO Sensors with Novel Intrinsic p-n Shifting and Ultrahigh Baseline Stability
(2024) Ajjaq, A.; Bulut, F.; Ozturk, O.; Acar, S.
Due to its stability, transportability, and ability to be produced using renewable energy sources, NH has become an attractive option for hydrogen production and storage. Detecting NH is then essential, being a toxic and flammable gas that can pose dangers if not properly monitored. ZnO chemiresistive sensors have shown great potential in real NH monitoring applications; yet, research and development in this area are ongoing due to reported limitations, like baseline instabilities and sensitivity to environmental factors, including temperature, humidity, and interferent gases. Herein, we suggest an approach to obtain sensors with competitive performance based on ZnO semiconducting metal oxides. For this purpose, one-dimensional nanostructured pure and La-doped ZnO films were synthesized hydrothermally. Incorporating large rare earth ions, like La, into the bulk lattice of ZnO is challenging and can lead to surface defects that are influential in gas-sensing reactions. The sensors experienced a temperature-induced p-n shifting at about 100 °C, verified by the Hall effect and AC impedance measurements. The doped sensor showed exceptional stepwise baseline stability and outstanding performance at a relatively low operating temperature (150 °C) with a sensing response of 91 at best (@ 50 ppm NH) and recorded a tolerance to water vapor up to 70% RH. Alongside p-n shifting, the enhanced performance was discussed in correlation with La doping-triggered changes in the nanostructural and surfacial properties of the films. We validated the proposed technique by producing similar sensors and performing multiple replicates to ensure consistency and reproducibility. We also introduced the fill factor concept into the gas sensor field as a new trustworthy parameter that could improve sensor performance assessment and help rate sensors based on deviation from ideality.
Burden and associated characteristics in caregivers of Parkinson's disease patients
(2024) Inaltekin, A.; Kocatürk, I.
Background: Parkinson's disease (PD) increases patient load and requirements of care. Determining the burden on PD patients' caregivers and associated factors may help to identify methods to reduce caregiver burden. This study investigated the factors associated with caregiver burden among PD patients caregivers. Methods: Eighty-five PD patients and 85 caregivers were included in the study. Zarit Burden Interview (ZBI) was used to measure caregiver burden; the Ways of Coping Scale (WCS) was used for coping; Modified Hoehn-Yahr Staging (MHYS) was used for staging patients. The International Parkinson and Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) parts 1 and 3 were used to evaluate non-motor and motor problems. Caregivers' depression and anxiety levels were evaluated with the Beck Depression Inventory and Beck Anxiety Inventory (BAI). Spearmen correlation coefficient was used to evaluate the relationship of variables with the ZBI score, and multiple linear regression analysis was used to determine the predictors of the ZBI score. Results: A positive significant relationship was found between the ZBI score and BAI score, MHYS score, WCS total score, and subscales: keeping to self, seeking refuge in fate, and seeking refuge in supernatural forces. MHYS score, WCS total score, BAI score, and MDS-UPDRS-1 were predictors of the ZBI score. Conclusions: The anxiety levels of caregivers, their ways of coping, and the patient's stage of the disease are important in caregiver burden. Coping ways can be changed to reduce the care burden. Developing psychological interventions for caregivers to change their coping styles can be important.
Effects of using collagen and aloe vera grafted fibroin scaffolds on osteogenic differentiation of rat bone marrow mesenchymal stem cells in SBF-enriched cell culture medium
(2023) Mohamed, S. A. T.; Emin, N.
In the study, collagen and aloe vera were grafted onto silk fibroin with two different methods, and 3D-microporous scaffolds were formed by lyophilization. Three osteogenic cultures were started by seeding rat bone marrow mesenchymal stem cells (MSC) and pre-induced MSC (OB) on biopolymeric scaffolds. The osteogenic medium was enriched with 10% (v/v) simulated body fluid (SBF) to promote mineralization and osteogenic differentiation in one of the MSC cultures and the OB culture. XRD, SEM, SEM-EDS analyses on cellular samples and histochemical (alizarin red, safranin-O, alcian blue) and immunohistochemical (anti-collagen-1, anti-osteocalcin, anti-osteopontin) staining showed that bone-like mineralization was occurred by both chemically and cellular activity. In addition, pre-osteogenic induction of MSCs in 2D-cultured was found to promote osteogenesis more rapidly when started 3D-cultured. These results indicated that enrichment of the cell culture medium with SBF is sufficient for in vitro mineralization rather than using high concentrations of SBF. The findings showed that OB cells on the 2F5C4A1 scaffold obtained the best osteogenic activity. Still, other culture media with 10% SBF content could be used for bone tissue engineering under osteogenic induction.
In-depth exploration of challenges faced by women in the Turkish maritime industry: A qualitative study
(2023) Yildirim, U.; Nart, S.; Akar, S.; Sarialioğlu, S.; Toygar, A.; Vardar, B.; Kaya, S.Ç.; Sari, M.
Background: Women are underrepresented in the maritime industry compared to men. This sector continues to perpetuate gender discrimination and stereotypes, often overlooking women's physical competence. Objective: To explore the multi-faceted challenges faced by Turkish female officers, unveiling the different dimensions of these challenges, and providing a comprehensive understanding of their experiences. Methods: In-depth semi-structured interviews were conducted with 40 Turkish female officers actively working on seagoing vessels. The data were analyzed using MAXQDA software. Results: The challenges faced by female officers were examined using content analysis. A total of 50 different codes were identified within 10 categories. The categories are gender inequality, violence, restriction of freedom, work-family conflict, mental health, physical differences, unsafe living space, insufficient communication with management, lack of psychometric testing and limited access to health services. Conclusion: By shedding light on the unique obstacles faced by female officers in Turkey, this study enhances our understanding of the underlying challenges and lays the groundwork for the implementation of effective policies and practices that promote the empowerment of women in the maritime industry.
Photoplethysmography-based assessment of varicose vein-related risk factors, exercise health beliefs, and venous refill time in healthcare professionals working in operating rooms and outpatient clinics
(2024) Şirin, G.; Cakir, S. K.; Eryiğit, S.; Toz, H.; Pirhan, O.; Taşabat, S. E.; Çalişkan, İ.
Bacground: Impaired venous return is observed in healthcare professionals who spend long periods standing and sitting. This descriptive cross-sectional study was conducted to evaluate varicose vein-related risk factors, exercise health beliefs, and venous refill time in healthcare professionals working in operating rooms and outpatient clinics by photoplethysmography. Method: The study sample consisted of 100 healthcare professionals without a diagnosis of peripheral venous insufficiency. Data were collected using a descriptive characteristics form, the Health Belief Model Scale for Exercise, the Short-Form McGill Pain Questionnaire, and photoplethysmography. Result: This study found that OR nurses had shorter venous refill times and experienced more pain due to prolonged standing, despite their high health beliefs about exercise. Conclusion: Healthcare professionals working in operating rooms should be screened for venous insufficiency and trained regarding the practices to prevent venous insufficiency, such as lying down, elevating legs, and using elastic stockings.
Soil respiration and controls in warmer winter: A snow manipulation study in postfire and undisturbed black pine forests
(2024) Pacaldo, R.S.; Aydin, M.; Amarille, R.K.
Climate change impacts drive warmer winters, reduced snowfall, and forest fires. In 2020, a wildfire scorched about 1508 hectares of black pine ( Arnold) forests in Türkiye. Whether the combined effects of lack of snow and forest fires significantly alter winter soil respiration (R) and soil temperature remains poorly understood. A field experiment was conducted in the postfire and undisturbed black pine forests during the winter to quantify R rates as affected by lack of snow and forest fire. We applied four treatments: snow-exclusion postfire (SEPF), snow postfire (SPF), snow-exclusion-undisturbed forest (SEUF), and snow undisturbed forest (SUF). The SEPF exhibited the significantly lowest mean R rates (0.71 μmol m s) compared to the SPF (1.02 μmol m s), SEUF (1.44 μmol m s), and SUF (1.48 μmol m s). The R also showed significant variations with time ( < .0001). However, treatments and time revealed no statistically significant interaction effects ( = .6801). Total winter R (January-March) ranged from 4.47 to 4.59 Mt CO ha in the undisturbed forest and 2.20 to 3.16 Mt CO ha in the postfire site. The R showed a significantly positive relationship ( < .0001) with the soil (0.59) and air (0.46) temperatures and a significantly negative relationship ( = .0017) with the soil moisture (-0.20) at the 5 cm depth. In contrast, the R indicated a negative but not statistically significant relationship ( = .0932) with the soil moisture (-0.16) at the 10 cm soil depth. The combined effects of lack of snow and forest fire significantly decreased R, thus conserving the soil's organic carbon stocks and reducing the CO contribution to the atmosphere. In contrast, a warmer winter significantly increased R rates in the undisturbed forest, suggesting an acceleration of soil organic carbon losses and providing positive feedback to climate change.
Use of Immunoglobulin Y Antibodies: Biosensor-based Diagnostic Systems and Prophylactic and Therapeutic Drug Delivery Systems for Viral Respiratory Diseases
(2024) Budama-Kilinc, Y.; Kurtur, O.B.; Gok, B.; Cakmakci, N.; Kecel-Gunduz, S.; Unel, N.M.; Ozturk, T.K.
Respiratory viruses have caused many pandemics from past to present and are among the top global public health problems due to their rate of spread. The recently experienced COVID-19 pandemic has led to an understanding of the importance of rapid diagnostic tests to prevent epidemics and the difficulties of developing new vaccines. On the other hand, the emergence of resistance to existing antiviral drugs during the treatment process poses a major problem for society and global health systems. Therefore, there is a need for new approaches for the diagnosis, prophylaxis, and treatment of existing or new types of respiratory viruses. Immunoglobulin Y antibodies (IgYs) obtained from the yolk of poultry eggs have significant advantages, such as high production volumes, low production costs, and high selectivity, which enable the development of innovative and strategic products. Especially in diagnosing respiratory viruses, antibody-based biosensors in which these antibodies are integrated have the potential to provide superiority in making rapid and accurate diagnosis as a practical diagnostic tool. This review article aims to provide information on using IgY antibodies in diagnostic, prophylactic, and therapeutic applications for respiratory viruses and to provide a perspective for future innovative applications.

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