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Advancing Semen Evaluation Using Lipidomics

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dc.contributor.authorEvans, Holly C.
dc.contributor.authorDinh, Thu T. N.
dc.contributor.authorHardcastle, Madison L.
dc.contributor.authorGilmore, Alicia A.
dc.contributor.authorUgur, Muhammet R.
dc.contributor.authorMustafa Hitit
dc.contributor.authorMustafa Hitit
dc.contributor.authorFrank Dean Jousan
dc.contributor.authorNicodemus, Molly C.
dc.contributor.authorErdogan Memili
dc.date.accessioned2026-01-04T15:17:12Z
dc.date.issued2021-04-16
dc.description.abstractDeveloping a deeper understanding of biological components of sperm is essential to improving cryopreservation techniques and reproductive technologies. To fully ascertain the functional determinants of fertility, lipidomic methods have come to the forefront. Lipidomics is the study of the lipid profile (lipidome) within a cell, tissue, or organism and provides a quantitative analysis of the lipid content in that sample. Sperm cells are composed of various lipids, each with their unique contribution to the overall function of the cell. Lipidomics has already been used to find new and exciting information regarding the fatty acid content of sperm cells from different species. While the applications of lipidomics are rapidly evolving, gaps in the knowledge base remain unresolved. Current limitations of lipidomics studies include the number of available samples to analyze and the total amount of cells within those samples needed to detect changes in the lipid profiles across different subjects. The information obtained through lipidomics research is essential to systems and cellular biology. This review provides a concise analysis of the most recent developments in lipidomic research. This scientific resource is important because these developments can be used to not only combat the reproductive challenges faced when using cryopreserved semen and artificial reproductive technologies in livestock such as cattle, but also other mammals, such as humans or endangered species.
dc.description.urihttps://doi.org/10.3389/fvets.2021.601794
dc.description.urihttps://www.frontiersin.org/articles/10.3389/fvets.2021.601794/pdf
dc.description.urihttps://pubmed.ncbi.nlm.nih.gov/33937366
dc.description.urihttp://dx.doi.org/10.3389/fvets.2021.601794
dc.description.urihttps://doaj.org/article/ace4e7a160f147c4a21b0060cc057cae
dc.description.urihttps://dx.doi.org/10.3389/fvets.2021.601794
dc.description.urihttps://aperta.ulakbim.gov.tr/record/238914
dc.identifier.doi10.3389/fvets.2021.601794
dc.identifier.eissn2297-1769
dc.identifier.openairedoi_dedup___::82c56bbb39e0a921850902c0208bc14b
dc.identifier.orcid0000-0003-1234-6693
dc.identifier.orcid0000-0002-2006-0612
dc.identifier.pubmed33937366
dc.identifier.scopus2-s2.0-85105226435
dc.identifier.urihttps://hdl.handle.net/20.500.12597/38720
dc.identifier.volume8
dc.identifier.wos000645449900001
dc.publisherFrontiers Media SA
dc.relation.ispartofFrontiers in Veterinary Science
dc.rightsOPEN
dc.subjectlipids
dc.subjectlivestock
dc.subjectVeterinary medicine
dc.subjectcryotolerance
dc.subjectSF600-1100
dc.subjectbiomarkers
dc.subjectVeterinary Science
dc.subjectfatty acids
dc.titleAdvancing Semen Evaluation Using Lipidomics
dc.typeArticle
dspace.entity.typePublication
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