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Newly isolated sporopollenin microcages from Platanus orientalis pollens as a vehicle for controlled drug delivery

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dc.contributor.authorMujtaba, Muhammad
dc.contributor.authorSargın, İdris
dc.contributor.authorAkyüz, Lalehan
dc.contributor.authorCeter, Talip
dc.contributor.authorKaya, Murat
dc.date.accessioned2026-01-03T10:08:36Z
dc.date.issued2017-08-01
dc.description.abstractSporopollenin microcages were produced from the pollens of Platanus orientalis. Paracetamol was loaded into the microcages. Pollen, sporopollenin, paracetamol and paracetamol-loaded sporopollenin microcages were characterized with FT-IR, TGA and SEM. The analytical analyses demonstrated that sporopollenin microcages were structurally intact, highly reticulated and thermally stable. The loading efficiency of the sporopollenin microcages was found to be 8.2% using the passive loading technique and 23.7% via evaporating loading technique. In vitro release and kinetics studies were performed to test the suitability of sporopollenin microcages for loading. These studies revealed that sporopollenin from P. orientalis can be suggested as a suitable carrier for drug loading and controlled release studies.
dc.description.urihttps://doi.org/10.1016/j.msec.2017.02.176
dc.description.urihttps://pubmed.ncbi.nlm.nih.gov/28532028
dc.description.urihttps://cris.vtt.fi/en/publications/329907d7-0f2a-4d87-ba80-4116b4f51cef
dc.description.urihttps://dx.doi.org/10.1016/j.msec.2017.02.176
dc.description.urihttps://hdl.handle.net/20.500.12451/4199
dc.identifier.doi10.1016/j.msec.2017.02.176
dc.identifier.endpage270
dc.identifier.issn0928-4931
dc.identifier.openairedoi_dedup___::dd1c942951aa36741da914cd37eb1d2d
dc.identifier.orcid0000-0001-8392-9226
dc.identifier.orcid0000-0003-3785-9575
dc.identifier.orcid0000-0001-8548-3037
dc.identifier.orcid0000-0003-3626-1758
dc.identifier.orcid0000-0001-6954-2703
dc.identifier.pubmed28532028
dc.identifier.scopus2-s2.0-85016422832
dc.identifier.startpage263
dc.identifier.urihttps://hdl.handle.net/20.500.12597/36512
dc.identifier.volume77
dc.identifier.wos000403381200030
dc.language.isoeng
dc.publisherElsevier BV
dc.relation.ispartofMaterials Science and Engineering: C
dc.rightsCLOSED
dc.subjectRelease kinetics
dc.subjectRelease Kinetics
dc.subjectCarotenoids
dc.subjectMicrocapsule
dc.subjectBiopolymers
dc.subjectDrug delivery
dc.subjectSpectroscopy, Fourier Transform Infrared
dc.subjectPollen
dc.subjectDrug Delivery
dc.subjectAcetaminophen
dc.subject.sdg3. Good health
dc.titleNewly isolated sporopollenin microcages from Platanus orientalis pollens as a vehicle for controlled drug delivery
dc.typeArticle
dspace.entity.typePublication
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