In vitro antimicrobial, antioxidant and antibiofilm activities of Bryum capillare, a bryophyte sample

Abstract

<p>The aim of this study is to determine antimicrobial, antioxidant and antibiofilm activities of Bryum capillare (BC), a bryophyte sample. BC samples were collected subjected to ethanol extraction after air drying. Antimicrobial activity was identified by determining the minimum inhibitory concentration (MIC) values. Antibiofilm activity of the extracts was tested against Staphylococcus aureus, Staphylococcus epidermidis and Candida albicans. Total phenolic compounds in the extracts were determined and antioxidant activities of the samples were identified by DPPH radical scavenging assay, metal chelating activity on ferrous ions and plasma lipid peroxidation inhibitory assay. As a result of the study, the MIC values were found to be &ge;125 &micro;g.mL-1 against all strains. In addition, BC extract showed 5% antibiofilm activity against only S. epidermidis. Total phenolic compounds were determined as 23,26 mg.g-1 and the results of DPPH radical scavenging activity, metal chelating activity on ferrous ions and plasma lipid peroxidation activity were found to be 15%, 3% and 4% respectively. As a result, it can be concluded that although the antimicrobial, antioxidant and antibiofilm activity of BC extracts were low, but further research is needed to be conducted for a detailed investigation.</p>