Yayın:
The potential protective effects of curcumin on the diabetic ovary: Experimental and molecular approaches

Basit Görünüm
dc.contributor.authorTufekci, Kıymet Kübra
dc.contributor.authorAltun, Gamze
dc.contributor.authorKipanyula, Maulilio John
dc.contributor.authorKaplan, Süleyman
dc.date.accessioned2026-01-04T19:53:24Z
dc.date.issued2024-01-01
dc.description.abstractDiabetes mellitus (DM) causes numerous systemic diseases in animals and humans. This may also lead to reproductive problems among individuals of reproductive age. Detrimental effects such as apoptosis in ovarian granulosa cells, degradation of communica-tion proteins, decreased oocyte quality, delayed meiotic maturation, and atrophy are among the increasing evidence that chronic hyperglycemia causes reproductive problems. Numerous studies have reported that the antidiabetic properties of the antioxidant curcumin may be due to its inhibition of oxidative stress, inflammation, and insulin resistance. There are also data indicating that curcumin reduces the risk of DM and its associated symptoms. This review discusses the protective or curative properties of curcumin in the treatment of DM-related problems in the ovary and seeks to elucidate potential underlying mechanisms. While the use of curcumin as a supportive/therapeutic agent has been introduced for the reduction of reproductive problems that may be caused by uncontrolled DM, more studies on this subject are needed.
dc.description.urihttps://doi.org/10.14670/HH-18-866
dc.description.urihttp://hdl.handle.net/10201/157040
dc.description.urihttps://doi.org/10.14670/hh-18-866
dc.identifier.doi10.14670/hh-18-866
dc.identifier.eissn1699-5848
dc.identifier.issn0213-3911
dc.identifier.openairedoi_dedup___::649bfcf54731ff643fa06251b41e577c
dc.identifier.pubmed39789984
dc.identifier.scopus2-s2.0-105008937885
dc.identifier.urihttps://hdl.handle.net/20.500.12597/41436
dc.identifier.volume40
dc.identifier.wos001530688800001
dc.language.isoeng
dc.publisherUniversidad de Murcia, Departamento de Biologia Celular e Histiologia
dc.relation.ispartofHistology and Histopathology
dc.rightsOPEN
dc.subjectCurcumin
dc.subjectDiabetes mellitus
dc.subjectCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología
dc.subjectOvary
dc.subjectFemale fertility
dc.titleThe potential protective effects of curcumin on the diabetic ovary: Experimental and molecular approaches
dc.typeArticle
dspace.entity.typePublication
local.api.response{"authors":[{"fullName":"Tufekci, Kıymet Kübra","name":"Kıymet Kübra","surname":"Tufekci","rank":1,"pid":null},{"fullName":"Altun, Gamze","name":"Gamze","surname":"Altun","rank":2,"pid":null},{"fullName":"Kipanyula, Maulilio John","name":"Maulilio John","surname":"Kipanyula","rank":3,"pid":null},{"fullName":"Kaplan, Süleyman","name":"Süleyman","surname":"Kaplan","rank":4,"pid":null}],"openAccessColor":null,"publiclyFunded":null,"type":"publication","language":{"code":"eng","label":"English"},"countries":null,"subjects":[{"subject":{"scheme":"keyword","value":"Curcumin"},"provenance":null},{"subject":{"scheme":"keyword","value":"Diabetes mellitus"},"provenance":null},{"subject":{"scheme":"keyword","value":"CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología"},"provenance":null},{"subject":{"scheme":"keyword","value":"Ovary"},"provenance":null},{"subject":{"scheme":"keyword","value":"Female fertility"},"provenance":null}],"mainTitle":"The potential protective effects of curcumin on the diabetic ovary: Experimental and molecular approaches","subTitle":null,"descriptions":["Diabetes mellitus (DM) causes numerous systemic diseases in animals and humans. This may also lead to reproductive problems among individuals of reproductive age. Detrimental effects such as apoptosis in ovarian granulosa cells, degradation of communica-tion proteins, decreased oocyte quality, delayed meiotic maturation, and atrophy are among the increasing evidence that chronic hyperglycemia causes reproductive problems. Numerous studies have reported that the antidiabetic properties of the antioxidant curcumin may be due to its inhibition of oxidative stress, inflammation, and insulin resistance. There are also data indicating that curcumin reduces the risk of DM and its associated symptoms. This review discusses the protective or curative properties of curcumin in the treatment of DM-related problems in the ovary and seeks to elucidate potential underlying mechanisms. While the use of curcumin as a supportive/therapeutic agent has been introduced for the reduction of reproductive problems that may be caused by uncontrolled DM, more studies on this subject are needed."],"publicationDate":"2024-01-01","publisher":"Universidad de Murcia, Departamento de Biologia Celular e Histiologia","embargoEndDate":null,"sources":["reponame:DIGITUM. Depósito Digital Institucional de la Universidad de Murcia","instname:Universidad de Murcia"],"formats":["application/pdf","20"],"contributors":["Departamento de Biologia Celular e Histiologia"],"coverages":null,"bestAccessRight":{"code":"c_abf2","label":"OPEN","scheme":"http://vocabularies.coar-repositories.org/documentation/access_rights/"},"container":{"name":"Histology and Histopathology","issnPrinted":"0213-3911","issnOnline":"1699-5848","issnLinking":null,"ep":null,"iss":null,"sp":null,"vol":"40","edition":null,"conferencePlace":null,"conferenceDate":null},"documentationUrls":null,"codeRepositoryUrl":null,"programmingLanguage":null,"contactPeople":null,"contactGroups":null,"tools":null,"size":null,"version":null,"geoLocations":null,"id":"doi_dedup___::649bfcf54731ff643fa06251b41e577c","originalIds":["oai:dnet:digitum_____::0e758aa6fbac029f4c501b8059aeed75","50|RECOLECTA___::55027bb4ba7d70fab000054e9a6c4bf3","50|medra_______::44dfcc8c0e35dc20d9a495423f79931f","10.14670/HH-18-866"],"pids":[{"scheme":"handle","value":"10201/157040"},{"scheme":"doi","value":"10.14670/hh-18-866"}],"dateOfCollection":null,"lastUpdateTimeStamp":null,"indicators":{"citationImpact":{"citationCount":0,"influence":2.5349236e-9,"popularity":2.4744335e-9,"impulse":0,"citationClass":"C5","influenceClass":"C5","impulseClass":"C5","popularityClass":"C5"}},"instances":[{"pids":[{"scheme":"handle","value":"10201/157040"}],"alternateIdentifiers":[{"scheme":"doi","value":"10.14670/hh-18-866"}],"license":"CC BY NC ND","type":"Article","urls":["https://doi.org/10.14670/HH-18-866","http://hdl.handle.net/10201/157040"],"publicationDate":"2025-01-01","refereed":"nonPeerReviewed"},{"pids":[{"scheme":"doi","value":"10.14670/hh-18-866"}],"type":"Article","urls":["https://doi.org/10.14670/hh-18-866"],"publicationDate":"2024-01-01","refereed":"nonPeerReviewed"}],"isGreen":null,"isInDiamondJournal":null}
local.import.sourceOpenAire
local.indexed.atWOS
local.indexed.atScopus
local.indexed.atPubMed

Dosyalar

Koleksiyonlar

Publications