Browsing by Author "Yilmaz, R."

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    Web of Science
    Detection of the lactic acid bacterial community in small scale white cheese processing facility using shotgun metagenomics and culturomics
    (2024.01.01) Cerit, Z.G.; Ilikkan, O.K.; Baloglu, M.C.; Yilmaz, R.
    This study aims to characterize lactic acid bacteria (LAB) community in small-scale white cheese processing facility highly favored by consumers. Shotgun metagenomics and culturomics based on MALDITOF MS approaches were employed. Samples from various production stages and equipment surfaces were collected. Dominant phyla in dairy and equipment samples were Firmicutes (63-70%) and Proteobacteria (84-89%), respectively. Lactococcus was the most abundant LAB genus across all samples, with Lactococcus lactis as dominant species followed by Streptococcus , Enterococcus , and Lactobacillus , indicating LAB community diversity contributing to product characteristics. Culturomics identi fied 12 LAB species, including Enterococcus faecalis and Lactobacillus delbrueckii . Metagenomics provided insights into microbial composition and dynamics in dairy environment, while culturomics identi fied speci fic LAB species. The combined approach offers a comprehensive view of dairy microbial communities, aiding industrial development by informing starter culture combinations for improved dairy products and processes. (c) 2024 Elsevier Ltd. All rights reserved.
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    Web of Science
    Evaluation of Patients with COVID-19 Followed Up in Intensive Care Units in the Second Year of the Pandemic: A Multicenter Point Prevalence Study
    (2024.01.01) Güngör, S.; Ediboglu, Ö.; Moçin, Ö.Y.; Adigüzel, N.; Tunçay, E.; Iscanli, I.G.E.; Er, B.; Karakurt, Z.; Turan, S.; Kosovali, B.D.; Mutlu, N.M.; Kayar, D.; Bektas, S.G.; Uysal, E.; Segmen, F.; Alp, G.; Erdem, D.; Selmi, N.H.; Güven, P.; Özçelik, Z.; Ocakcioglu, M.; Özgür, C.Y.; Yilmaz, R.; Özel, D.B.; Cebeci, H.; Güler, B.; Cansever, C.; Cakirca, M.; Inceöz, H.; Solmaz, I.; Sipahioglu, F.Ö.; Aydin, E.M.; Dayanir, H.; Öner, S.F.; Karatepe, U.; Özen, S.; Boran, M.; Ergül, D.F.; Kasapoglu, U.S.; Delen, L.A.; Toy, E.; Altun, K.; Albayrak, T.; Yanal, H.; Zaim, G.; Yarar, V.; Kilinç, G.; Deniz, M.; Özdemir, E.; Soylu, V.G.; Yilmaz, A.; Saygili, S.M.; Öztürk, E.K.; Ergan, B.; Eyüpoglu, S.; Sahin, Y.; Yüksel, B.; Bulut, A.; Saritas, A.; Yeniay, H.; Genç, M.; Kargin, F.; Özcan, O.; Karakoç, E.; Karaca, U.; Sözütek, D.; Sari, S.; Senoglu, N.; Aygün, H.; Yigit, A.C.; Kavruk, N.; Uzan, C.A.; Biçakcioglu, M.; Solak, S.; Özçelik, H.K.; Uluç, K.; Yildirim, I.; Arar, M.C.; Demirel, I.; Küver, S.U.; Özgür, E.S.; Aydin, K.; Dönmez, G.E.; Aygencel, G.; Esmaoglu, A.; Aydin, B.S.; Tokur, M.E.; Ekren, P.K.; Aydemir, Y.; Güney, B.Ç.; Erdil, Ö.Y.; Tünay, A.; Bahadir, T.; Uçkun, S.; Kocaoglu, N.; Pinar, H.U.; Karaca, N.K.; Gültekin, H.; Ayvat, P.; Özer, A.B.; Eroglu, A.; Kuyrukluyildiz, U.; Baytar, Ç.; Ayoglu, H.; Mizrakçi, S.; Metin, H.; Mutlu, O.P.Z.; Yilmaz, H.; Tüzüner, F.
    OBJECTIVE: A 1 -day point prevalence study was planned to obtain country data by determining the clinical characteristics, follow-up and treatment methods of coronavirus disease 2019 (COVID-19) cases that required intensive care unit (ICU) treatment in the second year of the pandemic. MATERIAL AND METHODS: All patients who were hospitalized in the ICUs due to COVID-19 between March 11, 2022, 08.00 AM, and March 12, 2022, 08.00 AM, were included in the study. Demographic characteristics, intensive care and laboratory data, radiological characteristics, and follow-up results of the patients were recorded. RESULTS: A total of 811 patients from 59 centers were included in the study, 59% of the cases were male, and the mean age was 74 +/- 14 years. At least one comorbid disease was present in 94% of the cases, and hypertension was the most common. When ICU weight scores were examined, Acute Physiology and Chronic Health Evaluation -II: 19 (15-27) and Sequential Organ Failure Assessment: 7 (4-10) were seen. Sepsis was present in 37% (n = 298) of cases. PaO2/FiO2 ratios of the patients were 190 the highest and 150 the lowest and 51% of the cases were followed via invasive mechanical ventilation. On the study day, 73% bilateral involvement was seen on chest x-ray, and ground -glass opacities (52%) were the most common on chest tomography. There was growth in culture in 40% (n = 318) of the cases, and the most common growth was in the tracheal aspirate (42%). CONCLUSION: The clinical course of COVID-19 is variable, and ICU follow-up was required due to advanced age, comorbidity, presence of respiratory symptoms, and widespread radiological involvement. The need for respiratory support and the presence of secondary infection are important issues to be considered in the follow-up. Despite the end of the second year of the pandemic and vaccination, the high severity of the disease as well as the need for follow-up in ICUs has shown that COVID-19 is an important health problem.