Browsing by Author "Topal, Kübra"

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    Effects of Nasal and Paranasal Sinus Variations on Chronic Otitis Media Development in Pediatric Patients.
    (2021-10-01T00:00:00Z) Efe Atila, Nihal; Topal, Kübra; Bulut, Yunus Emre; Kaya, Zülküf; Arslan, Berrin
    Chronic otitis media is an inflammatory disease of the middle ear. The airflow in the nasal passage affects the development of mastoid air cells through the eustachian tube.Nasal and paranasal pathologies and their anatomical variations cause chronic sinonasal inflammation and affect the middle ear mucosa. This study aims to reveal whether the nasal and paranasal sinus variations in pediatric patients are a factor in developing chronic otitis media.
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    Pubmed
    The Role of Manganese, Cadmium, Chromium and Selenium on Subjective Tinnitus.
    (2021-08-01T00:00:00Z) Atila, Nihal Efe; Atila, Alptug; Kaya, Zülküf; Bulut, Yunus E; Oner, Fatih; Topal, Kübra; Bayraktutan, Zafer; Bakan, Ebubekir
    Elevated levels of heavy metals like cadmium (Cd) and manganese (Mn) are known to lead to oxidative damage-related oto-toxicity and decreased levels of chromium (Cr) and selenium (Se) are known to lead to oto-toxicity due to reduced anti-oxidant activity. The aim of the present study was to evaluate serum levels of Cd, Mn, Cr, and Se and their relationship with tinnitus. A total of 48 patients with tinnitus (Group 1) and 40 healthy controls (Group 2) were included in the study. All participants were applied audiology tests. Severity of tinnitus was measured with Tinnitus Severity Index Questionnaire (TSIQ) in group 1. Serum Mn, Cd, Cr, and Se measurements were done by using The Agilent ICP-MS system consisted of a 7700 coupled plasma mass spectrometry (ICP-MS). Serum Cd, Mn, and Cr levels were higher in group 1 and Se level was lower in group 1 than that of group 2. We may conclude that Cd, Mn, Cr, and Se levels could play an important role in etio-pathogenesis of tinnitus, and thereby supplementation or reduction of these elements could be considered as novel therapeutic goals.