Browsing by Author "Sabaner, M.C."

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Comparative evaluation of 2D and 3D YouTube videos as supplementary educational resources for vitreoretinal surgery training
(2024) Yozgat, Z.; Sahin, H.K.; Dumlupinar, G.İ.; Sabaner, M.C.
Ophthalmologists and ophthalmology residents (ORs) are increasingly turning to the internet for medical information, underscoring the significant role that YouTube videos, particularly three-dimensional (3D) ones, play in lifelong learning. This study aimed to compare the content and quality of 3D YouTube videos with two-dimensional (2D) videos as supplementary educational tools for vitreoretinal surgery. Data collected included video length (minutes), time elapsed since upload (days), number of views, likes, dislikes, vitreoretinal surgery type, and visualization system. Video popularity and interaction were calculated using the video power index, interaction index, and viewing rate. Two senior ophthalmologists (SOs) and 2 ORs evaluated the videos using the DISCERN, Global Quality Score, and usefulness scoring systems. Inter-rater reliability was assessed using the intra-class correlation coefficient. A total of 392 videos were screened, with 67 2D and 67 3D videos deemed appropriate for inclusion. While 2D videos had significantly more views, likes, interaction index, and viewing rate than 3D videos (P < .001 for all), 3D videos were rated higher by ORs across all scoring systems (P < .05 for all). Inter-rater reliability was confirmed to be good, with the lowest intra-class correlation coefficient being 0.796 for SOs (95% confidence interval: 0.668-0.875) and 0.814 for ORs (95% confidence interval: 0.698-0.886). In conclusion, side-by-side 3D YouTube videos offer a valuable supplementary educational tool, enhancing depth perception and enabling both SOs and ORs to better understand the complexities of ocular surgeries, particularly vitreoretinal procedures. These videos can also be used to observe new procedures and refresh previously acquired knowledge of past surgeries.
One-Year Outcomes of Aflibercept in Treat-and-Extend Versus Pro Re Nata Regimens for Bevacizumab-Resistant Diabetic Macular Edema: A Real-World Study
(2024) Yozgat, Z.; Isik, M.U.; Sabaner, M.C.
Introduction: The aim of this study was to compare the efficacy of the treat-and-extend (TAE) regimen versus the pro re nata (PRN) regimen in patients with bevacizumab-resistant diabetic macular edema (DME) treated with aflibercept, with or without adjunctive laser therapy. Methods: Ninety-one eyes from 91 patients who were switched to aflibercept after three consecutive intravitreal bevacizumab injections for the treatment of DME were included in this retrospective real-world study. The patients were categorized into three groups: TAE (n = 30), TAE + laser (n = 31), and PRN (n = 30). Changes in best-corrected visual acuity and central macular subfield thickness (CMST) at 12, 24, and 52 weeks were defined as the primary functional and anatomical outcomes. Results: A total of 91 eyes from 91 patients (49.5% female) with a mean age of 63.9 ± 7.1 years were included in the analysis. At 52 weeks, the mean letter gains were 8.03, 8.90, and 10.23 in the TAE, TAE + laser, and PRN groups, respectively. Anatomical improvements, as measured by CMST reduction, were 55.33 µm, 33.35 µm, and 48.96 µm in the TAE, TAE + laser, and PRN groups, respectively. The average number of injections administered was 7.7, 8.1, and 8.1, respectively. The final extension interval for the TAE group was 8.7 weeks, compared to 9.5 weeks in the TAE + laser group. Conclusions: The PRN group demonstrated the highest functional improvement while the TAE group showed the greatest anatomical improvement. Overall, both anatomical and functional outcomes in the TAE regimen were comparable to the PRN regimen in patients with bevacizumab-resistant diabetic macular edema.
One-Year Outcomes of Aflibercept in Treat-and-Extend Versus Pro Re Nata Regimens for Bevacizumab-Resistant Diabetic Macular Edema: A Real-World Study
(2024.01.01) Yozgat, Z.; Isik, M.U.; Sabaner, M.C.
IntroductionThe aim of this study was to compare the efficacy of the treat-and-extend (TAE) regimen versus the pro re nata (PRN) regimen in patients with bevacizumab-resistant diabetic macular edema (DME) treated with aflibercept, with or without adjunctive laser therapy.MethodsNinety-one eyes from 91 patients who were switched to aflibercept after three consecutive intravitreal bevacizumab injections for the treatment of DME were included in this retrospective real-world study. The patients were categorized into three groups: TAE (n = 30), TAE + laser (n = 31), and PRN (n = 30). Changes in best-corrected visual acuity and central macular subfield thickness (CMST) at 12, 24, and 52 weeks were defined as the primary functional and anatomical outcomes.ResultsA total of 91 eyes from 91 patients (49.5% female) with a mean age of 63.9 +/- 7.1 years were included in the analysis. At 52 weeks, the mean letter gains were 8.03, 8.90, and 10.23 in the TAE, TAE + laser, and PRN groups, respectively. Anatomical improvements, as measured by CMST reduction, were 55.33 mu m, 33.35 mu m, and 48.96 mu m in the TAE, TAE + laser, and PRN groups, respectively. The average number of injections administered was 7.7, 8.1, and 8.1, respectively. The final extension interval for the TAE group was 8.7 weeks, compared to 9.5 weeks in the TAE + laser group.ConclusionsThe PRN group demonstrated the highest functional improvement while the TAE group showed the greatest anatomical improvement. Overall, both anatomical and functional outcomes in the TAE regimen were comparable to the PRN regimen in patients with bevacizumab-resistant diabetic macular edema.