Browsing by Author "Hekimoglu R."

Filter results by typing the first few letters
Now showing 1 - 1 of 1
  • No Thumbnail Available
    Scopus
    Alterations of Tear Film and Ocular Surface in Children with Type 1 Diabetes Mellitus
    (2020-04-02) Inanc M.; Kiziltoprak H.; Hekimoglu R.; Tekin K.; Ozalkak S.; Koc M.; Bayramoglu E.; Zirh S.; Yuruker S.; Aycan Z.
    Purpose: To investigate whether diabetes mellitus (DM) affects ocular surface of children with well-controlled type 1 DM. Methods: Sixty-five diabetic patients and 55 age-matched controls enrolled to study. Detailed ocular surface assessment including, ocular surface disease index (OSDI) questionnaire, tear film break-up time (TBUT) analysis, Schirmer test, and conjunctival impression cytologic analysis were performed. Results: Schirmer test and TBUT results were significantly lower in DM group than controls (p = 0.001, for all). OSDI scores of all participants were within normal range. Impression cytology analysis showed grade 0 changes in all participants and there was no difference between groups for goblet cell density (p > 0.05). The TBUT results were significantly associated with duration of DM (r = −0.309, p = 0.036). Conclusion: Diabetic children without symptoms, signs, and definite diagnosis of dry eye still had lower TBUT and Schirmer test results than controls; however, impression cytology analysis was similar in both groups.