Browsing by Author "Gür, Mahmut"

Now showing 1 - 4 of 4

Analysis of tautomeric equilibrium in (E)-4,6-dibromo-2-[(4-fluorophenylimino)methyl]-3-methoxyphenol compound.
(2015-12-05T00:00:00Z) Kaştaş, Çiğdem Albayrak; Kaştaş, Gökhan; Gür, Mahmut; Muğlu, Halit; Büyükgüngör, Orhan
In this study, the tautomeric equilibrium between the phenol-imine and keto-amine structural forms of (E)-4,6-dibromo-2-[(4-fluorophenylimino)methyl]-3-methoxyphenol compound has been investigated with experimental (XRD, UV-vis and NMR) and theoretical (DFT and TD-DFT) methods. The results clearly show that structural preference of the compound is definitely depended on its state. Namely, the compound exists in phenol-imine form in the solid state while one or both of these forms can be seen in solvent media. For example, the compound prefers phenol-imine form in benzene while both forms exist in EtOH and DMSO solvents. Coexistence of two forms has been quantified with NMR studies, giving a ratio of 11:9 for phenol and keto structures of the compound in acetone-d6 solvent.
Organic Fluorescent Compounds Based on Phenanthroimidazole: A Review on Highlights Studies.
(2023-07-25) Zurnacı, Merve; Şener, İzzet; Gür, Mahmut; Şener, Nesrin
Organic compounds containing phenanthroimidazole; Its optical, thermal, chemical, and high fluorescence have drawn the interest of numerous researchers. Phenanthroimidazole derivatives are appealing for various applications owing to these characteristics. This research provides a summary of the general information contained in studies on the synthesis, characterisation, photophysical characteristics, and possible applications of phenanthroimidazole derivative compounds. The focus of this study revolves around these topics' utilization in technological fields such sensors, solar cells, optical brighteners, and OLED, which covers significant studies on mentioned topics. We anticipate that this study is meant to provide an outline for researchers aiming to further examine fluorescent organic compounds for technological innovations. Furthermore, we anticipate that this research will be crucial in developing long term high organic compounds for optoelectronic devices.
Study on Photophysical Properties of Novel Fluorescent Phenanthroimidazole-Thiadiazole Hybrid Derivatives.
(2022-05-01T00:00:00Z) Zurnacı, Merve; Şener, İzzet; Gür, Mahmut; Şener, Nesrin
Phenanthroimidazole-thiadiazole hybrid derivatives, which are new heterocyclic compounds with fluorescence properties, were synthesized by designing a two-step reaction mechanism and their photophysical properties were investigated. The synthesized derivatives were purified and their structures were elucidated by ATR-IR, H-NMR, elemental analysis and HR-MS methods. In the next stage of the study, the absorption and emission spectra of the synthesized new phenanthroimidazole-thiadiazole hybrid derivatives were determined by UV-Vis and fluorescence spectroscopy. Stokes' shifts, molar extinction coefficients (ε), singlet energy levels (Es), quantum yield (ϕ), lifetimes (τ), the radiative (k) and the nonradiative (k) constant for new hybrid derivatives were measured in DMSO. In addition, aggregation measurements, which is an important parameter that changes the photophysical properties were performed and for these compounds, structure: photophysical properties were discussed.
Synthesis and characterization of new 1,3,4-thiadiazole derivatives: study of their antibacterial activity and CT-DNA binding.
(2022-10-17T00:00:00Z) Sayiner, Hakan S; Yilmazer, Mehmet I; Abdelsalam, Aisha T; Ganim, Mohamed A; Baloglu, Cengiz; Altunoglu, Yasemin Celik; Gür, Mahmut; Saracoglu, Murat; Attia, Mohamed S; Mahmoud, Safwat A; Mohamed, Ekram H; Boukherroub, Rabah; Al-Shaalan, Nora Hamad; Alharthi, Sarah; Kandemirli, Fatma; Amin, Mohammed A
1,3,4-Thiadiazole molecules (1-4) were synthesized by the reaction of phenylthiosemicarbazide and methoxy cinnamic acid molecules in the presence of phosphorus oxychloride, and characterized with UV, FT-IR, C-NMR, and H-NMR methods. DFT calculations (b3lyp/6-311++G(d,p)) were performed to investigate the structures' geometry and physiochemical properties. Their antibacterial activity was screened for various bacteria strains such as , ATCC 13048, , , , and Gram positive such as ATCC 25923, ATCC 7644, , , ATCC, , , , alfa , and found to have an inhibitory effect on and , while molecules 1, 3 and 4 had an inhibitory effect on and alpha . The experimental results were supported by the docking study using the Kinase ThiM from . All the investigated compounds showed an inhibitory effect for the protein. In addition, the mechanism of the 1-4 molecule interaction with calf thymus-DNA (CT-DNA) was investigated by UV-vis spectroscopic methods.