Browsing by Author "Duman H."

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    Cytotoxic compounds from endemic arnebia purpurea
    (2015-04-01) Yuzbasioglu M.; Kuruuzum-Uz A.; Guvenalp Z.; Simon A.; Tóth G.; Sebnem Harput U.; Kazaz C.; Bilgili B.; Duman H.; Saracoglu I.; Omur Demirezer L.
    Phytochemical studies of the roots and aerial parts of endemic Arnebia purpurea S. Erik &H. Sumbul resulted in the isolation and characterization of four naphthoquinones [isovalerylalkannin (1), α-methyl-n-butanoyl alkannin (2), acetylalkannin (3), and alkannin (4)], a triterpene derivative [3-O-acetyl-oleanolic acid (5)], a steroid [â-sitosterol (6)], three flavonoid glycosides [isorhamnetin-3-O-rutinoside (7), kaempferol-3-O-rutinoside (8), kaempferol 3-O-(5"-acetyl) apiofuranoside 7-O-rhamnopyranoside (9)] and a phenolic acid [rosmarinic acid (10)]. 3-O-Acetyl-oleanolic acid, isorhamnetin-3-O-rutinoside, kaempferol-3-O-rutinoside, and kaempferol 3-O-(5"-acetyl) apiofuranoside 7-O-rhamnopyranoside are reported from an Arnebia species for the first time. Cytotoxic activities on L929 murine fibrosarcoma cell line of the isolated compounds were investigated using MTT assay. Naphthoquinones (1-4) showed intermediate cytotoxic activity in comparison with the standard, doxorubicin.
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    Dichoropetalum alanyensis (Apiaceae), a new species from South Anatolia, Turkey
    (2016-01-01) Bilgili B.; Sağiroğlu M.; Şeker M.; Duman H.
    Dichoropetalum alanyensis Bilgili, Sağıroğlu & H.Duman, a new species from South Anatolia in Turkey (Antalya-Alanya), is described and illustrated. It is closely related to D. chryseum (Boiss. & Heldr. ex Boiss.) Pimenov & Kljuykov, from which it differs mainly by its habit, basal leaves and lobes, and mericarp features. Diagnostic morphological characters are discussed. Notes are also given on its ecology and conservation status, together with scanning electron micrographs of mericarp surface sculpturing pattern. ITS sequences were used for DNA fingerprinting. The data were analyzed with the SEAVIEW package. Standardized data were used to generate a dendrogram that revealed the phylogenetic relationships of taxa in tribes Selineae (Dichoropetalum-Johrenia), Tordylieae (Cymbocarpum), and Bupleureae (Diplotaenia) from different localities.