Browsing by Author "Celik, Muhammet"

Filter results by typing the first few letters
Now showing 1 - 1 of 1
  • No Thumbnail Available
    Pubmed
    Role of Endothelin 1 on Proliferation and Migration of Human MCF-7 Cells.
    (2020-10-01T00:00:00Z) Cinar, Irfan; Yayla, Muhammed; Celik, Muhammet; Bilen, Arzu; Bayraktutan, Zafer
    The aim of this study was to explore the role of endothelin 1 (ET-1) in human breast cancer proliferation and migration and antagonism of endothelin receptor A (ETAR) and endothelin receptor B (ETBR) by using the non-selective dual ETA/ETB receptor antagonist bosentan and determine its anti-proliferative, anti-metastatic, and apoptotic effects demonstrated by nuclear factor kappa B (NF-kB), vascular endothelial growth factor (VEGF), Caspase 3 and Caspase 9 expression on endothelin-induced proliferation of MCF-7 cell line in vitro.