Browsing by Author "Altuner E.M."

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Antimicrobial screening of mnium stellare
(2015-04-11) Canli K.; Altuner E.M.; Akata I.
Many plants contain active substances that are known to be effective in both enhancing the wound healing process and lowering the incidence of wound infections. Previous studies have shown that bryophytes produce a variety of secondary metabolites that present pharmaceutical activities including antimicrobial activity against various pathogenic bacteria and fungi. The aim of this study was to investigate the antimicrobial activity of Mnium stellare against 17 bacterial and 1 fungal strains. Our present study has shown that the ethanol extract of M. stellare has antimicrobial activity against several Gram positive and Gram negative microorganism tested, but its antimicrobial activity is notable especially against B. subtilis, S. typhimirium, S. aureus, S. carnosus, and S. epidermidis. These results are the very first report of the antimicrobial activity of M. stellare.
Biochemical and Antioxidant Properties as well as Antimicrobial and Antibiofilm Activities of Allium scorodoprasum subsp. jajlae (Vved.) Stearn
(2023-06-01) Canli K.; Turu D.; Benek A.; Bozyel M.E.; Simsek Ö.; Altuner E.M.
In this study, the chemical composition and biological activity of Allium scorodoprasum subsp. jajlae (Vved.) Stearn were investigated for the first time, focusing on its antimicrobial, antioxidant, and antibiofilm properties. A GC-MS analysis was employed to evaluate the composition of its secondary metabolites, identifying linoleic acid, palmitic acid, and octadecanoic acid 2,3-dihydroxypropyl ester as the major compounds in ethanol extract. The antimicrobial activity of A. scorodoprasum subsp. jajlae was assessed against 26 strains, including standard, food isolate, clinical isolate, and multidrug-resistant ones, as well as three Candida species using the disc diffusion method and the determination of the minimum inhibitory concentration (MIC). The extract showed strong antimicrobial activity against Staphylococcus aureus strains, including methicillin-resistant and multidrug-resistant strains, as well as Candida tropicalis and Candida glabrata. Its antioxidant capacity was evaluated using the DPPH method, revealing a high level of antioxidant activity in the plant. Additionally, the antibiofilm activity of A. scorodoprasum subsp. jajlae was determined, demonstrating a reduction in biofilm formation for the Escherichia coli ATCC 25922 strain and an increase in biofilm formation for the other tested strains. The findings suggest potential applications of A. scorodoprasum subsp. jajlae in the development of novel antimicrobial, antioxidant, and antibiofilm agents.
Biochemical composition and in vitro antimicrobial activity of endemic helichrysum arenarium ssp. aucheriethanol extract
(2021-02-01) Bozyel M.E.; Canli K.; Benek A.; Yetgin A.; Altuner E.M.
The phenomenon of using plants for therapeutic purposes dates back to the earlier times in the history of humanity. Even though there have been remarkable developments in the modern medicine, pharmaceutical, and chemical industries, the therapeutic use of medicinal plants is still up to date. Due to the emergence of antibiotic-resistant strains and the proliferation of side effects in synthetic drugs, the importance of research on the antimicrobial potential and biochemical composition of plant extracts has increased. The main purpose of this present study is to screen both the antibacterial and antifungal activity of endemic Helichrysum arenarium ssp. aucheri ethanol extract by disk diffusion on some Gram-negative and Gram-positive bacteria and Candida albicans, and to identify the major compounds found in the ethanol extract by GC/MS. According to the results obtained from the study, it can be proposed that the extract showed antibacterial and anti-fungal activity for all microorganisms excluding Salmonella typhimurium SL1344, Salmonella infantis, E. coli (food isolate), Escherichia coli ATCC 25922 and Enterobacter aerogenes ATCC 13048, and some chemical compounds were detected, which may be responsible for the antimicrobial activity.
BIOCHEMICAL COMPOSITION, AND IN VITRO ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF SALVIA FRUTICOSA, AN ETHNOMEDICINAL PLANT
(2023-01-01) Bozyel M.E.; Canli K.; Benek A.; Simsek O.; Akata I.; Altuner E.M.
Biochemical, Antioxidant Properties and Antimicrobial Activity of Epiphytic Leafy Liverwort Frullania dilatata (L.) Dumort
(2023-05-01) Simsek O.; Canli K.; Benek A.; Turu D.; Altuner E.M.
In this study, the biochemical, antioxidant properties, and antimicrobial activity of the epiphytic leafy liverwort Frullania dilatata (L.) Dumort were investigated. Due to the scarcity and difficulty in obtaining liverworts, research on their bioactivity is limited; thus, this study aimed to uncover the potential of F. dilatata. The antimicrobial activity was evaluated against various microorganisms, including food isolates, clinical isolates, multidrug-resistant strains, and standard strains, using the disk diffusion method and determining the minimum inhibitory concentration (MIC) values. This study represents the first antioxidant investigation on F. dilatata and an antimicrobial study using ethanol extract and the disk diffusion method. Notably, susceptibility was observed in Enterococcus faecalis ATCC 29212, Enterococcus faecium FI, Listeria monocytogenes ATCC 7644, Providencia rustigianii MDR, and Staphylococcus aureus ATCC 25923. The antioxidant capacity was assessed using the DPPH method, emphasizing the high scavenging performance. Gas chromatography-mass spectrometry (GC-MS) analysis identified the primary compounds as frullanolide (19.08%), 2,3-Dimethylanisole (15.21%), linoleic acid (11.11%), palmitic acid (9.83%), and valerenic acid (5.3%). The results demonstrated the significant antimicrobial activity of F. dilatata against the tested microorganisms and its potent antioxidant properties. These findings emphasize the potential of F. dilatata as a promising source of natural antimicrobial and antioxidant agents, underscoring the importance of further investigation into its bioactive compounds and elucidating the mechanisms of action in future studies.
Biochemical, Antioxidant Properties and Antimicrobial Activity of Steno-Endemic Origanum onites
(2023-08-01) Canli K.; Bozyel M.E.; Turu D.; Benek A.; Simsek O.; Altuner E.M.
Biofilm inhibiting phytometabolites
(2023-01-01) Altinöz E.; Şenturan M.; Altuner E.M.
Biofilms are produced by some microorganisms to attach to any surface. These layers are mainly exopolysaccharide (EPS) in nature, but they also contain water, protein, and nucleic acids. One of the most important functions of this matrix is to protect microorganisms against drastic changes in some environmental factors such as UV light, water activity, osmotic pressure, pH, radiation, and the presence of antimicrobial agents. In addition to being one of the main reasons for several diseases, which affect public health, biofilm is also responsible for several significant issues in livestock, agriculture, food industries, and ventilation and irrigation systems. The most common procedures used to prevent the formation or removal of biofilms completely, which were already formed, include limiting nutrients required for microbial growth, sterilization of surface materials to prevent bacterial attachment, or removing biofilms by chemical or mechanical treatments. However, microorganisms that have the ability to form biofilms exhibit behaviors different from other microorganisms in terms of their growth rates and resistance to antibiotic or antifungal treatments. Besides, increasing resistance to antibiotics or antifungal agents in biofilm-forming microorganisms leads to remarkable problems in preventing biofilm formation or removing biofilms which are already formed. Thus, scientists are researching to discover novel agents which can be used for both inhibiting biofilm formation and removing it. Research presented that several phytometabolites have a great potential of being used as antibiofilm agents. This chapter aims to present some detailed information about biofilms and to review the research about the potential of phytometabolites as antibiofilm agents.
Biological Activities and Biochemical Composition of Endemic Achillea fraasii
(2023-04-01) Tunca-Pinarli Y.; Benek A.; Turu D.; Bozyel M.E.; Canli K.; Altuner E.M.
In this study, we investigated the antimicrobial, antioxidant, and antibiofilm activities and the biochemical composition of Achillea fraasii. The antimicrobial activity of A. fraasii ethanol extract (AFEt) was tested against 48 strains, and this is the first study testing the antimicrobial activity of this plant to this extent. The antioxidant activity was determined using the DPPH assay, and the antibiofilm activity of A. fraasii aqueous extract (AFAq) against five strains was assessed. The chemical composition of the plant extract was determined using GC-MS with artemisia ketone (19.41%) as the main component. The findings indicated that AFEt displayed antimicrobial activity against 38 strains, with a particular efficacy observed against various Staphylococcus aureus strains, such as S. aureus ATCC 25923, clinically isolated, multidrug resistant (MDR), and methicillin-resistant (MRSA) strains. In addition, the highest activity was observed against Enterococcus faecium. Moreover, the extract demonstrated activity against Candida strains. The plant extract also showed relatively good antioxidant activity compared to ascorbic acid, with an EC50 value of 55.52 µg/mL. However, AFAq acted as a biofilm activator against Escherichia coli ATCC 25922, increasing the biofilm formation by 2.63-fold. In conclusion, our study demonstrates the potential of A. fraasii as a source of antimicrobial and antioxidant agents.
Chemical composition and in vitro antimicrobial activity of matthiola tricuspidata ethanol extract
(2021-10-01) Canli K.; Bozvel M.E.; Benek A.; Yetgin A.; Senturan M.; Altuner E.M.
It is widely acccptcd by scientists that innovation of new antimicrobial agents has extreme im-portance for the sake of the tiiturc of human beings; therefore the researches about the antimicrobial potentials of plant extracts and their biochemical composition have great importance. This present study aims to investigate the antimicrobial activity of Mat-thiola tricuspidata ethanol extract against several Gram-positive and Gram-negative microorganisms and Candida albicans by disk diffusion method, and to identity its chemical composition by GasChroma-tography-Mass Spectrometry. As a result, it was observed that the cxtract showed activity for all microorganisms excluding Enterobacter aerogenes ATCC 13048, Escherichia coli ATCC 25922, E. coli, Klebsiella pneumoniae, Salmonella infantis, and Salmonella typhimurium SL1344 and some chcmical compounds were dctcctcd, which may be responsible for the antimicrobial activity.
Chitosan Loses Innate Beneficial Properties after Being Dissolved in Acetic Acid: Supported by Detailed Molecular Modeling
(2020-12-14) Bilican I.; Pekdemir S.; Onses M.S.; Akyuz L.; Altuner E.M.; Koc-Bilican B.; Zang L.S.; Mujtaba M.; Mulerčikas P.; Kaya M.
Chitosan, which is obtained via deacetylation of chitin, has a variety of uses in agriculture, food, medicine, pharmaceuticals, and cosmetics. Industrial chitosan is in a gel form, which is produced by dissolving in acetic acids. These gels can be chitosan-only films or composite films that include other ingredients such as plant extracts or other polymers. Chitosan-based films, however, are not as natural as chitosan dissolved in weak acids, and they lack some of chitosan's innate properties. In this study, natural chitosan films (NCFs) were obtained from the pupa shells of black soldier flies through a process that maintains the original structure. The semisynthetic film (SCF) was then produced by dissolving the same NCF in acetic acid along with glycerol and glutaraldehyde. The semisynthetic film remarkably lost the beneficial properties of the natural film. The deteriorated characteristics include hydrophobicity, crystallinity, thermal properties, as well as a loss of fibril structure and a reduction in bacterial attachment. Moreover, the Ag-deposited NCFs manifested strikingly higher surface-enhanced Raman scattering activity as compared with the semisynthetic ones. These results, including the molecular modeling data, demonstrate that dissolving chitosan in acetic acid changes its polymeric structure.
Correlation between chlorophyll degradation and the amount of heavy metals found in pseudevernia furfuracea in kayseri (Turkey)
(2011-06-14) Yildiz A.; Aksoy A.; Akbulut G.; Demirezen D.; Islek C.; Altuner E.M.; Duman F.
Air pollution and associated heavy metal pollution, is an important environmental problem. One of the methods used to monitor heavy pollution in the air is the method of transplanting lichen samples by the bag technique. In this study, Pseudevernia furfuracea was used as a bioindicator to determine the heavy metal level of air pollution heavy metal level in Kayseri and to generate an air pollution map of the city. The lichen samples were collected from the Yaprakli̇ Mountains in Çanki̇ri̇ in 2002 and transplanted to 10 different stations in Kayseri. Lichen samples were re-collected at two different periods in three month intervals. Inductively coupled plasma (ICP) spectrometry was used to identify the heavy metals, such as Cu, Cd, Mn, Ni, Pb and Zn in the lichen samples. The chlorophyll a and b contents were determined by using the DMSO method. With these values chlorophyll a+b, a/b and b/a were also calculated. According to the heavy metal analysis results of Pseudevernia furfuracea, which worked well as a bioindicator, air pollution in Kayseri due to industry, heating and traffic was observed. The concentration of Cd at the 3rd and 9th station, Cu concentration at the 1st and 8th station, Mn concentration at the 3rd and 10th and Pb concentration at the 3rd, 8th and 10th station were considerably high. In addition to these, the concentration of Zn was observed high at 9th station.
DNA protection, antioxidant, antibacterial and enzyme inhibition activities of heartwood and sapwood extracts from juniper and olive woods
(2015-08-21) Özkan O.E.; Zengin G.; Akça M.; Baloʇlu M.C.; Olgun Ç.; Altuner E.M.; Ateş S.; Aktümsek A.; Vurdu H.
In this study, DNA protective, antioxidant, antibacterial and enzyme inhibiting properties of methanol extracts obtained from juniper and olive heartwood and sapwood were determined. These extracts were tested by five antioxidant methods (DPPH scavenging, FRAP, CUPRAC, metal chelating and phosphomolybdenum). Generally, heartwood extracts of both species are more efficient for DPPH radical scavenging activity, cupric ion reducing activity, ferric reducing antioxidant power and metal chelating activity than sapwood extracts. When compared to heartwood extracts, sapwood extracts have larger inhibition zone in disk diffusion test. In addition, all extracts showed high antibacterial activity against Staphylococcus aureus. DNA protection of both extracts had a capacity to inhibit the DNA damage arisen from Fenton's reagent. The highest DNA protective activity was observed in juniper sapwood extract with 84%. Furthermore, other extracts also indicated more than 60% of DNA protective activity. Olive wood extracts displayed the strongest enzyme inhibition activities against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Although juniper heartwood extracts showed highest anti-amylase, anti-glucosidase and anti-tyrosinase effects, they had no ability for inhibition BChE. The methanol extracts of olive samples demonstrated the most antioxidant activity (DPPH, CUPRAC and FRAP). In addition, juniper samples showed the highest anti-amylase, anti-tyrosinase, metal chelating and DNA protective activity. According to these results, the extracts of juniper and olive wood can be considered as a source of natural bio active agents for dietary, pharmacological and medicinal applications. This research will also serve as a base for future studies about biological activities of wood extracts.
Effect of high hydrostatic pressure on seed germination, microbial quality, anatomy-morphology and physiological characteristics of garden cress (Lepidium sativum) seedlings
(2013-06-01) Işlek C.; Altuner E.M.; Çeter T.; Alpas H.
High hydrostatic pressure is a non-thermal food processing technology that is found to increase the percentage of germination, decrease the germination time and improve the microbial quality of seeds. In this study, pressures of 100-400 MPa for 10 min at 30°C are used to compare the percentage of germination, the microbial quality of seeds, chlorophyll a and b, and total phenolic compounds concentrations in seedlings, and the anatomy-morphology characteristics of garden cress. Enhanced reductions of total aerobic mesophilic bacteria, total and fecal coliforms, and yeast and mould populations in seeds were observed, especially at 300 MPa. In addition, the percentage of germination, chlorophyll content and phenolic compounds concentrations, fresh and dry weights, and hypocotyl lengths of the seedlings are higher than those of all samples, where the percentage of germination is equal to controls but higher than other samples, and radicula length is lower than controls but higher than others. © 2013 Copyright Taylor and Francis Group, LLC.
Effect of storage temperature on the chemical and microbiological properties of white cheese from Kastamonu, Turkey
(2020-01-01) Eljagmani S.; Altuner E.M.
In Turkey, white cheese is a popular choice among the consumers and comprises about 60% of the entire domestic produce. Certain cheese varieties are endemic and commercially unavailable due to socioeconomic factors. In this study, five different types of white cheese were collected from the city of Kastamonu; one as a factory-packed brand, three as local-market open products, and one produced in a farm from cow milk. The study aimed to investigate the shelf-life of the cheese samples stored at 5, 15 and 25 °C. The microbiological and chemical tests were carried out regularly on 1, 7, 14, 21 and 28 days of storage at 5, 15 and 25 °C. The shelf-lives were reportedly found to be between the days 14 and 28. The pH values were high in all cases, with no significant decrease with changes in storage duration. Conversely, the salt contents were low on day 1 and decreased during the storage at different temperatures. Microbiological examinations revealed relatively high growth of microorganisms such as coliforms, Salmonella, and Staphylococci post-storage. In addition to bacterial growth, storage at increasing temperatures also led to changes in the sensory attributes such as appearance, texture, aroma and taste of the cheese.
In Vitro antimicrobial activity screening of xylaria hypoxylon
(2016-01-01) Canli K.; Akata I.; Altuner E.M.
Background: Fungi have a potential of using both as nutritive and medicinal food stuff. Because of containing several therapeutic agents, they are reported to be used for hundreds of years to treat several diseases caused by bacteria, fungi, viruses and parasites. The aim of this study is to determine the in vitro antimicrobial activity of Xylaria hypoxylon, which were collected from Yomra, Trabzon, Turkey. Materials and Methods: X. hypoxylon samples were air dried and extracted by using ethanol. Antimicrobial activity of X. hypoxylon ethanol extracts were investigated against 21 bacterial and 2 fungal strains, namely, Bacillus subtilis DSMZ 1971, Bacillus subtilis ATCC 6633, Candida albicans ATCC 10231, Candida albicans DSMZ 1386, Enterobacter aerogenes ATCC 13048, Enterococcus durans, Enterococcus faecalis ATCC 29212, Enterococcus faecium, Escherichia coli ATCC 25922, Escherichia coli CFAI, Klebsiella pneumoniae, Listeria innocula, Listeria monocytogenes ATCC 7644, Pseudomonas aeruginosa DSMZ 50071, Pseudomonas fluorescence P1, Salmonella enteritidis ATCC 13075, Salmonella infantis, Salmonella kentucky, Salmonella typhimurium SL 1344, Staphylococcus aureus ATCC 25923, Staphylococcus carnosus MC1.B, Staphylococcus epidermidis DSMZ 20044 and Streptococcus agalactiae DSMZ 6784 by using the disk diffusion method. Results: It is observed that ethanol extracts of X. hypoxylon has antimicrobial activity against several Gram positive and Gram negative microorganisms tested. As a result of the study, an antimicrobial activity of X. hypoxylon found against most of strains used in the study. Conclusion: The results of our study clearly puts forward that X. hypoxylon could have a possible medicinal use.
In vitro antimicrobial screening of Aquilaria agallocha roots
(2016-01-01) Canlı K.; Yetgin A.; Akata I.; Altuner E.M.
Background: It was previously shown that some parts of Aquilaria agallocha, which is commonly known as oud or oodh, such as roots have been used as a traditional medical herbal in different countries. In Turkey A. agallocha is one of the ingredients while preparing famous Mesir paste, which was invented as a medicinal paste and used from the Ottoman period to now at least for 500 years. The identification the in vitro antimicrobial activity of ethanol extract of A. agallocha roots is main purpose of this analysis. Materials and Methods: By using 17 bacteria and 1 fungi, which include Bacillus, Candida, Enterobacter, Enterococcus, Escherichia, Klebsiella, Listeria, Pseudomonas, Salmonella and Staphylococcus genera, the activity of A. agallocha root extracts were analysed by the help of the disk diffusion method, that is one of the methods commonly used to determine antimicrobial activities. Results: As a result of the study it was observed that ethanol extracts of A. agallocha roots have a clear antimicrobial activity against nearly all microorganism used in the study, but only two bacteria namely E. coli ATCC 25922 and S. typhimurium SL 1344. Conclusion: According to the disk diffusion test results it may be possible to propose that A. agallocha roots should have a medicinal uses especially against E. faecium, L. monocytogenes ATCC 7644, B. subtilis DSMZ 1971, C. albicans DSMZ 1386, S. epidermidis DSMZ 20044 and S. aureus ATCC 25923.
In vitro antimicrobial screening of Hedwigia ciliata Var. leucophaea and determination of the ethanol extract composition by gas chromatography/mass spectrometry (GC/MS)
(2014-08-01) Canli K.; Cetin B.; Altuner E.M.; Türkmen Y.; Uzek U.; Dursun H.
Many plants contain active substances that are known to be effective in both enhancing the wound healing process and lowering the incidence of wound infections. Previous studies have shown that bryophytes produce a variety of secondary metabolites that present pharmaceutical activities including antimicrobial activity against various pathogenic bacteria and fungi. The aim of this study was to investigate the antimicrobial activity of Hedwigia ciliata var. leucophaea (He) against 17 bacterial and 1 fungal strains and analyse the composition by GC/MS. He samples were collected from Akdag Mountain (Amasya, TURKEY) and subjected to ethanol extraction after air drying. The in vitro antimicrobial activities of He extracts having 9 mg.mL-1 concentrations were assessed against a wide range of strains by disk diffusion method and the results were supported by a MIC (minimum inhibitory concentration) test. Our present study has shown that the ethanol extract of He has antimicrobial activity against several Gram positive and Gram negative microorganisms tested, but its antimicrobial activity is notable especially against B. subtilis, E. faecalis, S. camosus, and S. epidermidis. These results are the very first report of the antimicrobial activity of He and its.composition. The results obtained herein indicate that ethanol extract of He contains several active metabolites and it is active against several microorganisms. But further researches, especially cytotoxicity and genotoxicity tests are needed to be conducted to conclude whether He extracts can be used safely in terms of their antimicrobial activity.
Investigation of antifungal activity of ononis spinosa L ASH used for the therapy of skin infections as folk remedies
(2010-01-01) Altuner E.M.; Çeter T.; Lşlek C.
Traditional folk remedies used for centuries come up focus of interest in recent years, due to the trend of use of herb-derived natural products. In addition, increasing morbidity and mortality rates of opportunistic fungal infections and accelerating antifungal resistance rates of fungi lead to the use of alternative therapies with herb-derived preparations as novel antifungals. Ononis spinosa L. (spiny restharrow), which is classified in Leguminosae family, is one of the plants used in herbal medicine as folk remedies for the treatment of skin lesions and/or infections as well as many other disorders. Antibacterial, antifungal, anti-inflammatory and analgesic effects of Ononis spinosa (OS) have already been supported by different studies. The roots and aerial sections of OS are the mainly employed parts for application, however local communities inhabiting at southeastern parts of Anatolia, Turkey, employ the ashes of OS widely to heal the skin infections. There have been no reports about the antifungal activity of OS ashes as far as the current literature is concerned. The aim of this study was to investigate the antifungal activity of ashes of OS, collected from a rural area located at Southeast Anatolia. Ashes of OS have been obtained by burning the plant samples at 400̈C, and extracted in sterile distilled water and ethanol. The efficacy of aqueous and ethanol extracts of OS ashes were tested against 10 fungi, of which one was a Candida albicans standard strain (ATCC 95071) and the others were clinical isolates (C.albicans, Candida glabrata, Candida tropicalis, Candida krusei, Candida guilliermondii, Candida parapsilosis, Candida pelliculosa, Trkhosporon asahii, Trichophyton rubrum). Antifungal susceptibility test was performed by disc diffusion (DD) method and the results were confirmed with minimum inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) values determined by microdilution method. The results indicated that both aqueous and ethanol extracts of OS ash showed antifungal activity against C. albicans ATCC 95071 (DD inhibition zones were 16 and 15 mm, respectively; MIC= 1.25 ug/ml, MFC= 1.25 ug/ml), whereas against C.glabrata clinical isolate only ethanol extract exhibited antifungal activity (DD inhibition zone= 10 mm, MIC= 5.00 ug/ml, MFC= 40.00 ug/ml). No antifungal effect was detected against the other clinical Candida spp, T.asahii and T.rubrum isolates. In conclusion, since our results emphasize that extracts of OS ash that traditionally used for skin disorders, showed promising degrees of antifungal activity against some of Candida strains, these preliminary data should be supported by further large-scale studies.
New Bis-1,3,4-Thiadiazoles Based on Fumaric Acid: Preparation, Structure Elucidation, Antibacterial Activities, and Quantum-Chemical Studies
(2023-01-01) Muğlu H.; Yakan H.; Elefkhakry G.A.I.; Altuner E.M.; Serdar Çavuş M.
Potential of High Hydrostatic Pressure to Improve the Production of Plants Used as Food
(2018-01-26) Altuner E.M.
High hydrostatic pressure (HHP) is one of the nonthermal food treatment practices. While using HHP in food processing, the food samples are sealed in its final package and subjected to a high level of isostatic pressure. The pressure applied on food samples ranges from 100 to 800MPa or in some cases even higher pressures, where water is used as a pressure-transmitting medium. HHP is used in food processing for several purposes, such as sterilization, coagulation, and gelation. Besides food processing, there are some other potential uses of HHP in different areas, such as conducting HHP on plants used as food to change some physiological and biochemical properties, which can be accepted as an improvement, when it is compared to the unpressurized plant samples. In addition, since HHP is a nonthermal food treatment method, it does not destroy the embryo in the seeds to some extent, which can, in contrast, be observed after thermal processing. Thus, HHP can be used safely to process the plant seeds.In this chapter, the potential of HHP on improving the production of plants used as food will be discussed.