Browsing by Author "Akata, Ilgaz"

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    Pubmed
    A new pollen-derived microcarrier for pantoprazole delivery.
    (2017-02-01T00:00:00Z) Akyuz, Lalehan; Sargin, Idris; Kaya, Murat; Ceter, Talip; Akata, Ilgaz
    Plant-derived carriers have emerged as promising materials for drug encapsulation. Especially, sporopollenin microcapsules extracted from diverse pollen species have been proved to be effective drug carriers due to their biocompatibility, homogeneity in size, resistance to harsh chemical conditions and high thermal stability. Here in this study, sporopollenin microcapsules were isolated successfully from the pollens of a common tree (Corylus avellana, the European hazelnut) and used as a carrier for pantoprazole (PaNa) (a proton pump inhibitor). The drug entrapment efficiency was recorded as 29.81%. SEM micrographs clearly showed the drug was loaded into the microcapsules through the apertures of microcapsule and also some drugs were adsorbed on the surface of microcapsules. FT-IR spectra analysis confirmed the drug loading. Thermogravimetric analysis revealed that thermal stability of PaNa was enhanced by encapsulation. In vitro release studies showed that PaNa-loaded sporopollenin microcapsules exhibited better release performance than the control. C. avellana sporopollenin microcapsules can make an efficient carrier for delivery of PaNa.
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    Pubmed
    ANTIMICROBIAL SCREENING OF ROOTS.
    (2016-08-12) Canlı, Kerem; Yetgin, Ali; Akata, Ilgaz; Altuner, Ergin Murat
    It was previously shown that some parts of , which is commonly known as oud or oodh, such as roots have been used as a traditional medical herbal in different countries. In Turkey is one of the ingredients while preparing famous Mesir paste, which was invented as a medicinal paste and used from the Ottoman period to now at least for 500 years. The identification the antimicrobial activity of ethanol extract of roots is main purpose of this analysis.
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    Pubmed
    IN VITRO ANTIMICROBIAL ACTIVITY SCREENING OF XYLARIA HYPOXYLON
    (2016-07-03) Canli, Kerem; Akata, Ilgaz; Altuner, Ergin Murat
    Fungi have a potential of using both as nutritive and medicinal food stuff. Because of containing several therapeutic agents, they are reported to be used for hundreds of years to treat several diseases caused by bacteria, fungi, viruses and parasites. The aim of this study is to determine the antimicrobial activity of , which were collected from Yomra, Trabzon, Turkey.