Chemical Composition and Antimicrobial Activities of Cold-Pressed Oils Obtained From Nettle, Radish and Pomegranate Seeds

Abstract

Abstract 
 
 Aim of study: The aim of
 this study is to put forward the antimicrobial activity of cold pressed oils
 obtained from seeds of nettle (Urtica
 dioica), radish (Raphanus sativus)
 and pomegranate (Punica granatum).
 
 Material and
 Methods: Oils of
 these seeds were analysed for their antibacterial and antifungal activities by
 the disk diffusion and MIC tests against fifteen microorganisms, Staphylococcus epidermidis DSMZ 20044, Staphylococcus aureus ATCC 25923, Salmonella typhimurium SL 1344, Salmonella kentucky, Salmonella infantis, Salmonella enteritidis, Pseudomonas fluorescens P1 ATCC 13075, Pseudomonas aeruginosa DSMZ 50071, Klebsiella pneumoniae, Escherichia coli ATCC 25922, Enterococcus faecium, Enterococcus faecalis ATCC 29212, Enterobacter aerogenes ATCC 13048, Candida albicans DSMZ 1386 and Bacillus subtilis DSMZ 1971. The results
 were compared against 11 standard antibiotics, which are cefazolin,
 clindamycin, chloramphenicol, ciprofloxacin, amoxicillin/clavulanic acid,
 sulfamethoxazole/trimethoprim, ceftriaxone, gentamicin, ampicillin, cephalothin,
 cefuroxime and vancomycin. The extracts were also chemically analysed by using
 GC-MS.
 
 Main results: As a result, radish oil is observed to be active
 against all microorganisms with the highest activity, where nettle oil is
 active against all microorganisms except for S. epidermidis. The lowest activity was observed in pomegranate
 oil.
 
 Highlights: The results of the study clearly puts forward that
 oils obtained from nettle, radish and pomegranate could have a possible
 medicinal use.