Yayın:
Molecular analysis of the env, LTR, and pX regions of bovine leukemia virus in dairy cattle of Türkiye

Basit Görünüm
dc.contributor.authorDuran-Yelken, Selda
dc.contributor.authorAlkan, Feray
dc.date.accessioned2026-01-04T20:05:45Z
dc.date.issued2024-02-14
dc.description.abstractBovine leukemia virus is a retrovirus that causes enzootic bovine leukosis and is associated with global economic losses in the livestock industry. The aim of this study was to investigate the genotype determination of BLVs from cattle housed in 6 different farms in Türkiye and the characterization of their LTR and pX (tax, rex, R3, and G4 gene) regions. For this purpose, blood samples from 48 cattle infected with BLV were used. The phylogenetic analysis based on the env gene sequences revealed that all BLVs were clustered in genotype 1 (G1), and the sequences of the LTR (n = 48) and the pX region (n = 33) of BLVs were obtained. Also, analysis of these nucleic acid and amino acid sequences allowed assessments similar to those reported in earlier studies to be relevant to transactivation and pathogenesis. This study reports the molecular analysis of the LTR and pX region of BLVs in Türkiye for the first time.
dc.description.urihttps://doi.org/10.1007/s11262-024-02058-7
dc.description.urihttps://pubmed.ncbi.nlm.nih.gov/38355991
dc.identifier.doi10.1007/s11262-024-02058-7
dc.identifier.eissn1572-994X
dc.identifier.endpage185
dc.identifier.issn0920-8569
dc.identifier.openairedoi_dedup___::c60c57b5c35cd5b3208f4b738244fac4
dc.identifier.orcid0000-0003-0633-3132
dc.identifier.orcid0000-0003-3854-6503
dc.identifier.pubmed38355991
dc.identifier.scopus2-s2.0-85185125361
dc.identifier.startpage173
dc.identifier.urihttps://hdl.handle.net/20.500.12597/41575
dc.identifier.volume60
dc.identifier.wos001161635800001
dc.language.isoeng
dc.publisherSpringer Science and Business Media LLC
dc.relation.ispartofVirus Genes
dc.rightsCLOSED
dc.subjectTurkey
dc.subjectLeukemia Virus, Bovine
dc.subjectAnimals
dc.subjectCattle
dc.subjectAmino Acid Sequence
dc.subjectGenes, env
dc.subjectPhylogeny
dc.titleMolecular analysis of the env, LTR, and pX regions of bovine leukemia virus in dairy cattle of Türkiye
dc.typeArticle
dspace.entity.typePublication
local.api.response{"authors":[{"fullName":"Selda Duran-Yelken","name":"Selda","surname":"Duran-Yelken","rank":1,"pid":{"id":{"scheme":"orcid","value":"0000-0003-0633-3132"},"provenance":null}},{"fullName":"Feray Alkan","name":"Feray","surname":"Alkan","rank":2,"pid":{"id":{"scheme":"orcid_pending","value":"0000-0003-3854-6503"},"provenance":null}}],"openAccessColor":null,"publiclyFunded":false,"type":"publication","language":{"code":"eng","label":"English"},"countries":null,"subjects":[{"subject":{"scheme":"keyword","value":"Turkey"},"provenance":null},{"subject":{"scheme":"keyword","value":"Leukemia Virus, Bovine"},"provenance":null},{"subject":{"scheme":"keyword","value":"Animals"},"provenance":null},{"subject":{"scheme":"keyword","value":"Cattle"},"provenance":null},{"subject":{"scheme":"keyword","value":"Amino Acid Sequence"},"provenance":null},{"subject":{"scheme":"keyword","value":"Genes, env"},"provenance":null},{"subject":{"scheme":"keyword","value":"Phylogeny"},"provenance":null}],"mainTitle":"Molecular analysis of the env, LTR, and pX regions of bovine leukemia virus in dairy cattle of Türkiye","subTitle":null,"descriptions":["Bovine leukemia virus is a retrovirus that causes enzootic bovine leukosis and is associated with global economic losses in the livestock industry. The aim of this study was to investigate the genotype determination of BLVs from cattle housed in 6 different farms in Türkiye and the characterization of their LTR and pX (tax, rex, R3, and G4 gene) regions. For this purpose, blood samples from 48 cattle infected with BLV were used. The phylogenetic analysis based on the env gene sequences revealed that all BLVs were clustered in genotype 1 (G1), and the sequences of the LTR (n = 48) and the pX region (n = 33) of BLVs were obtained. Also, analysis of these nucleic acid and amino acid sequences allowed assessments similar to those reported in earlier studies to be relevant to transactivation and pathogenesis. This study reports the molecular analysis of the LTR and pX region of BLVs in Türkiye for the first time."],"publicationDate":"2024-02-14","publisher":"Springer Science and Business Media LLC","embargoEndDate":null,"sources":["Crossref"],"formats":null,"contributors":null,"coverages":null,"bestAccessRight":{"code":"c_14cb","label":"CLOSED","scheme":"http://vocabularies.coar-repositories.org/documentation/access_rights/"},"container":{"name":"Virus Genes","issnPrinted":"0920-8569","issnOnline":"1572-994X","issnLinking":null,"ep":"185","iss":null,"sp":"173","vol":"60","edition":null,"conferencePlace":null,"conferenceDate":null},"documentationUrls":null,"codeRepositoryUrl":null,"programmingLanguage":null,"contactPeople":null,"contactGroups":null,"tools":null,"size":null,"version":null,"geoLocations":null,"id":"doi_dedup___::c60c57b5c35cd5b3208f4b738244fac4","originalIds":["2058","10.1007/s11262-024-02058-7","50|doiboost____|c60c57b5c35cd5b3208f4b738244fac4","38355991"],"pids":[{"scheme":"doi","value":"10.1007/s11262-024-02058-7"},{"scheme":"pmid","value":"38355991"}],"dateOfCollection":null,"lastUpdateTimeStamp":null,"indicators":{"citationImpact":{"citationCount":1,"influence":2.5607076e-9,"popularity":3.2537837e-9,"impulse":1,"citationClass":"C5","influenceClass":"C5","impulseClass":"C5","popularityClass":"C5"}},"instances":[{"pids":[{"scheme":"doi","value":"10.1007/s11262-024-02058-7"}],"license":"Springer Nature TDM","type":"Article","urls":["https://doi.org/10.1007/s11262-024-02058-7"],"publicationDate":"2024-02-14","refereed":"peerReviewed"},{"pids":[{"scheme":"pmid","value":"38355991"}],"alternateIdentifiers":[{"scheme":"doi","value":"10.1007/s11262-024-02058-7"}],"type":"Article","urls":["https://pubmed.ncbi.nlm.nih.gov/38355991"],"publicationDate":"2024-03-29","refereed":"nonPeerReviewed"}],"isGreen":false,"isInDiamondJournal":false}
local.import.sourceOpenAire
local.indexed.atWOS
local.indexed.atScopus
local.indexed.atPubMed

Dosyalar

Koleksiyonlar

Publications