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The Effect of 900-Megahertz Electromagnetic Field Exposure in the First and Middle Adolescent Period on the Spleen in Male Rats: A Biochemical and Histopathological Study

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dc.contributor.authorİKİNCİ KELEŞ, Ayşe
dc.contributor.authorSAPMAZ, Tuğçe
dc.contributor.authorEROL, Hüseyin Serkan
dc.contributor.authorBİTERGE SÜT, Burcu
dc.contributor.authorKELEŞ, Gökhan
dc.contributor.authorODACİ, Ersan
dc.contributor.authorPOLAT, Sait
dc.contributor.authorHALICI, Mesut Bünyami
dc.date.accessioned2026-01-04T13:39:18Z
dc.date.issued2019-12-30
dc.description.abstractAim: Adolescents are at risk due to the intensive use of mobile phones. The aim of this study was to investigate the histopathological and biochemical effects of 900-Megahertz electromagnetic field on spleen in late adolescent period, exposed during periods of early and mid-adolescence.Material and Methods: In this study, 24 Sprague Dawley 21-day-old male rats were divided into control (n=8), sham (n=8) and electromagnetic field groups (n=8). Control group rats were not subjected to any application. Electromagnetic field group rats were taken into the electromagnetic field cage and were exposed to 900-Megahertz electromagnetic field (1 hour per day for 25 days). Sham group rats were taken into the electromagnetic field cages but were not exposed to electromagnetic field. At the end of the treatment, all animals were sacrificed by cervical dislocation method and the spleens were removed. After histological procedures, tissue sections were taken and stained with hematoxylin-eosin and periodic acid Schiff. Histopathological evaluation was performed on the spleen tissues. Oxidative stress parameters including lipid peroxidation, superoxide dismutase, glutathione and catalase levels were investigated via biochemical analysis.Results: Histopathological evaluation revealed megakaryocyte cells, enlarged white pulps and dilated sinusoids in spleen tissues of adolescent rats in electromagnetic field group. According to biochemical analysis results, it was determined that glutathione and lipid peroxidation values were increased, but superoxide dismutase and catalase values were decreased.Conclusion: It can be said that the 900-Megahertz electromagnetic field applied in adolescent period caused morphological changes on spleen tissue and caused oxidative stress in male rats.
dc.description.urihttps://doi.org/10.18678/dtfd.608616
dc.description.urihttps://dergipark.org.tr/tr/download/article-file/909990
dc.description.urihttps://dx.doi.org/10.18678/dtfd.608616
dc.description.urihttps://search.trdizin.gov.tr/tr/yayin/detay/497011
dc.description.urihttps://hdl.handle.net/11480/11591
dc.identifier.doi10.18678/dtfd.608616
dc.identifier.eissn1307-671X
dc.identifier.endpage196
dc.identifier.openairedoi_dedup___::4f37a9986188a679966ca41d046150e5
dc.identifier.orcid0000-0003-0716-5695
dc.identifier.orcid0000-0001-6927-3582
dc.identifier.orcid0000-0002-9121-536x
dc.identifier.orcid0000-0001-5756-5756
dc.identifier.orcid0000-0002-4875-9820
dc.identifier.orcid0000-0002-4644-477x
dc.identifier.orcid0000-0003-1646-8831
dc.identifier.orcid0000-0002-7473-2955
dc.identifier.scopus2-s2.0-85077561066
dc.identifier.startpage192
dc.identifier.urihttps://hdl.handle.net/20.500.12597/37640
dc.identifier.volume21
dc.publisherDuzce Medical Journal
dc.relation.ispartofDüzce Tıp Fakültesi Dergisi
dc.rightsOPEN
dc.subjectAdolescent
dc.subjectOxidative stress
dc.subjectElectromagnetic field
dc.subjectSpleen
dc.subject.sdg3. Good health
dc.titleThe Effect of 900-Megahertz Electromagnetic Field Exposure in the First and Middle Adolescent Period on the Spleen in Male Rats: A Biochemical and Histopathological Study
dc.typeArticle
dspace.entity.typePublication
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