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Exploring the Nutraceutical Potential of Dried Pepper Capsicum annuum L. on Market from Altino in Abruzzo Region

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dc.contributor.authorDella Valle, A.
dc.contributor.authorDimmito, M. P.
dc.contributor.authorZengin, G.
dc.contributor.authorPieretti, S.
dc.contributor.authorMollica, A.
dc.contributor.authorLocatelli, M.
dc.contributor.authorCichelli, A.
dc.contributor.authorNovellino, E.
dc.contributor.authorAk, G.
dc.contributor.authorYerlikaya, S.
dc.contributor.authorBaloglu, M. C.
dc.contributor.authorAltunoglu, Y. C.
dc.contributor.authorStefanucci, A.
dc.date.accessioned2026-01-04T14:08:08Z
dc.date.issued2020-05-08
dc.description.abstractSweet pepper is a typical type of Capsicum annuum from Abruzzo region, recognized as a traditional and local product, traditionally cultivated in the town of Altino (Abruzzo region, Italy). The aim of this study is to compare the sweet type of peppers from Altino with the hot pepper cultivated in the same area, in order to delineate their different phytochemical and biological profiles in vitro and in vivo. In this study, we elucidated their phytochemical composition, fatty acids composition and phenolic/flavonoid contents in extracts. Then antioxidant and enzyme inhibition assays were performed to evaluate their biological properties, together with in vitro cell assay and in vivo anti-inflammatory activity. Microwave (1000 mg/mL) extract of hot pepper showed the best inhibition value on in vitro cell growth assay; in fact, the number of survived cells was about 20% and 40% for microwave and Soxhlet extracts, respectively. In vivo anti-inflammatory assay revealed good activity for both species, which, when associated with in vitro cell inhibition results, could explain the protective effect on human prostatic hyperplasia.
dc.description.urihttps://doi.org/10.3390/antiox9050400
dc.description.urihttps://www.mdpi.com/2076-3921/9/5/400/pdf
dc.description.urihttps://pubmed.ncbi.nlm.nih.gov/32397242
dc.description.urihttp://dx.doi.org/10.3390/antiox9050400
dc.description.urihttps://doaj.org/article/7548649422f3448db567080120590c55
dc.description.urihttps://dx.doi.org/10.3390/antiox9050400
dc.description.urihttps://www.mdpi.com/2076-3921/9/5/400
dc.description.urihttps://hdl.handle.net/11564/724201
dc.identifier.doi10.3390/antiox9050400
dc.identifier.eissn2076-3921
dc.identifier.openairedoi_dedup___::d0ddaa03453fe4b6aadf30e03194944d
dc.identifier.orcid0000-0002-9381-7196
dc.identifier.orcid0000-0001-6548-7823
dc.identifier.orcid0000-0001-5926-6194
dc.identifier.orcid0000-0002-7242-4860
dc.identifier.orcid0000-0002-0840-825x
dc.identifier.orcid0000-0002-2987-5738
dc.identifier.orcid0000-0002-5349-7298
dc.identifier.orcid0000-0003-2976-7224
dc.identifier.orcid0000-0001-7525-2913
dc.identifier.pubmed32397242
dc.identifier.scopus2-s2.0-85087924461
dc.identifier.startpage400
dc.identifier.urihttps://hdl.handle.net/20.500.12597/37965
dc.identifier.volume9
dc.identifier.wos000539284200043
dc.language.isoeng
dc.publisherMDPI AG
dc.relation.ispartofAntioxidants
dc.rightsOPEN
dc.subjectnutraceuticals
dc.subject<i>Capsicum annuum</i>
dc.subjectchemical composition
dc.subjectTherapeutics. Pharmacology
dc.subjectRM1-950
dc.subjectfunctional ingredients
dc.subjectCapsicum annuum
dc.subjectnutraceuticals
dc.subjectchemical composition
dc.subjectfunctional ingredients Asphodeline-Aanatolica
dc.subjectprostate-cancer
dc.subjectinflammation
dc.subjectcapsaicin
dc.subjectprofile
dc.subjectArticle
dc.subject.sdg3. Good health
dc.titleExploring the Nutraceutical Potential of Dried Pepper Capsicum annuum L. on Market from Altino in Abruzzo Region
dc.typeArticle
dspace.entity.typePublication
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