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Biochemical, Antioxidant Properties and Antimicrobial Activity of Steno-Endemic Origanum onites

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dc.contributor.authorCanli, Kerem
dc.contributor.authorBozyel, Mustafa Eray
dc.contributor.authorTuru, Dilay
dc.contributor.authorBenek, Atakan
dc.contributor.authorSimsek, Ozcan
dc.contributor.authorAltuner, Ergin Murat
dc.date.accessioned2026-01-04T19:04:26Z
dc.date.issued2023-08-02
dc.description.abstractOriganum onites (Lamiaceae) is an Eastern Mediterranean plant that is widely used in Turkish traditional medicine. This study aimed to investigate the biochemical composition, antimicrobial activity, and antioxidant potential of O. onites. In this study, the biochemical composition of the O. onites ethanol extract (OOEt) was analyzed using GC-MS. The antimicrobial activity was investigated using a disk diffusion test and determining minimum inhibitory concentrations (MIC) against 30 microorganism strains, including 28 bacteria (some multidrug-resistant) and 2 fungi. Additionally, the antioxidant activity was evaluated using the DPPH method. The main component identified was carvacrol. OOEt demonstrated antimicrobial activity against a wide range of tested microorganism strains. OOEt displayed the highest activity against E. faecium (a Gram-positive bacterium) at 100 µL with a 52 mm inhibition zone. Additionally, P. aeruginosa DSMZ 50071 and P. fluorescens P1, which are Gram-negative bacteria, were the most sensitive strains with a 24 mm inhibition zone in 100 µL of OOEt. The data obtained from A. baumannii (a multidrug-resistant strain) is particularly striking, as higher activity was observed compared to all positive controls. All tested fungal strains showed more effective results than positive controls. The antioxidant activity of OOEt was found to be stronger than that of the positive control, ascorbic acid. This study determined that O. onites has significant antimicrobial and antioxidant potential.
dc.description.urihttps://doi.org/10.3390/microorganisms11081987
dc.description.urihttps://pubmed.ncbi.nlm.nih.gov/37630547
dc.description.urihttp://dx.doi.org/10.3390/microorganisms11081987
dc.description.urihttps://doaj.org/article/081c8b86f3c3495bb54505d08d2d0564
dc.description.urihttps://dx.doi.org/10.3390/microorganisms11081987
dc.description.urihttps://avesis.deu.edu.tr/publication/details/d73258e2-ff34-45ab-bfc0-6633f28cf44c/oai
dc.description.urihttps://avesis.comu.edu.tr/publication/details/d73258e2-ff34-45ab-bfc0-6633f28cf44c/oai
dc.identifier.doi10.3390/microorganisms11081987
dc.identifier.eissn2076-2607
dc.identifier.openairedoi_dedup___::17a85b00669857af65dd635cf5518cf8
dc.identifier.orcid0000-0001-5556-4880
dc.identifier.orcid0000-0002-8485-0488
dc.identifier.orcid0000-0001-6726-5968
dc.identifier.orcid0000-0002-3210-7641
dc.identifier.orcid0000-0001-5351-8071
dc.identifier.pubmed37630547
dc.identifier.scopus2-s2.0-85168923263
dc.identifier.startpage1987
dc.identifier.urihttps://hdl.handle.net/20.500.12597/40950
dc.identifier.volume11
dc.identifier.wos001056893300001
dc.language.isoeng
dc.publisherMDPI AG
dc.relation.ispartofMicroorganisms
dc.rightsOPEN
dc.subjectQH301-705.5
dc.subject<i>Origanum onites</i>
dc.subjectantioxidant activity
dc.subjectantimicrobial activities
dc.subjectBiology (General)
dc.subject<i>Origanum onites</i>
dc.subjectantimicrobial activities
dc.subjectantioxidant activity
dc.subjectArticle
dc.subject.sdg6. Clean water
dc.subject.sdg3. Good health
dc.titleBiochemical, Antioxidant Properties and Antimicrobial Activity of Steno-Endemic Origanum onites
dc.typeArticle
dspace.entity.typePublication
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