Inanc, Merve, Kiziltoprak, Hasan, Hekimoglu, Rumeysa, Tekin, Kemal, Ozalkak, Servan, Koc, Mustafa, Bayramoglu, Elvan, Zirh, Selim, Yuruker, Sinan, Aycan, ZehraInanc M., Kiziltoprak H., Hekimoglu R., Tekin K., Ozalkak S., Koc M., Bayramoglu E., Zirh S., Yuruker S., Aycan Z.Inanc, M, Kiziltoprak, H, Hekimoglu, R, Tekin, K, Ozalkak, S, Koc, M, Bayramoglu, E, Zirh, S, Yuruker, S, Aycan, Z2023-05-092023-05-092020-04-022020-04-022020.01.010927-3948https://hdl.handle.net/20.500.12597/13186: To investigate whether diabetes mellitus (DM) affects ocular surface of children with well-controlled type 1 DM.: Sixty-five diabetic patients and 55 age-matched controls enrolled to study. Detailed ocular surface assessment including, ocular surface disease index (OSDI) questionnaire, tear film break-up time (TBUT) analysis, Schirmer test, and conjunctival impression cytologic analysis were performed.: Schirmer test and TBUT results were significantly lower in DM group than controls ( = 0.001, for all). OSDI scores of all participants were within normal range. Impression cytology analysis showed grade 0 changes in all participants and there was no difference between groups for goblet cell density ( > 0.05). The TBUT results were significantly associated with duration of DM ( = -0.309, = 0.036).: Diabetic children without symptoms, signs, and definite diagnosis of dry eye still had lower TBUT and Schirmer test results than controls; however, impression cytology analysis was similar in both groups.Purpose: To investigate whether diabetes mellitus (DM) affects ocular surface of children with well-controlled type 1 DM. Methods: Sixty-five diabetic patients and 55 age-matched controls enrolled to study. Detailed ocular surface assessment including, ocular surface disease index (OSDI) questionnaire, tear film break-up time (TBUT) analysis, Schirmer test, and conjunctival impression cytologic analysis were performed. Results: Schirmer test and TBUT results were significantly lower in DM group than controls (p = 0.001, for all). OSDI scores of all participants were within normal range. Impression cytology analysis showed grade 0 changes in all participants and there was no difference between groups for goblet cell density (p > 0.05). The TBUT results were significantly associated with duration of DM (r = −0.309, p = 0.036). Conclusion: Diabetic children without symptoms, signs, and definite diagnosis of dry eye still had lower TBUT and Schirmer test results than controls; however, impression cytology analysis was similar in both groups.falsedry eyeimpression cytologymellitusocular surfacetear filmdry eye | impression cytology | mellitus | ocular surface | tear filmComparative Study10.1080/09273948.2019.157121210.1080/09273948.2019.15712122-s2.0-85062375175WOS:00052644330000530806526362369281744-5078