Hasan YAKANTemel Kan BAKIRHalit MUĞLU2023-04-142023-04-142020-02-01Yakan, H., Bakir, T., Muğlu, H. (2020). Synthesis, spectroscopic studies, and antioxidant activities of novel thio/carbohydrazones and bis-isatin derivatives from terephthalaldehyde. Turkish Journal of Chemistry, 44(1), 237-2481300-0527https://search.trdizin.gov.tr/publication/detail/335157/synthesis-spectroscopic-studies-and-antioxidant-activities-of-novel-thiocarbohydrazones-and-bis-isatin-derivatives-from-terephthalaldehydehttps://hdl.handle.net/20.500.12597/7275New bis(isatins-thio/carbohydrazones) based on Schiff bases were prepared from terephthalaldehyde biscarbohydrazone and 5-substituted isatins in the presence of a drop of sulfuric acid under reflux in ethanol. Terephthalaldehyde bis(thio/carbohydrazone) was synthesized by the reaction of (thio)/carbohydrazide and terephthalaldehyde inthe presence of a few drops of acetic acid under reflux in ethanol. The structures of these synthesized compounds weredetermined using IR, 1 H NMR, and 13 C NMR spectroscopy and elemental analysis. The in vitro antioxidant activityof all the compounds was determined by the 1,1-diphenyl-2-picryl hydrazyl (DPPH.) free radical scavenging method.Compound 2 showed the best antioxidant activity.enginfo:eu-repo/semantics/openAccessRESEARCH10.3906/kim-1910-133351572372484411303-6130