Özülken, Kemal, Aksoy Aydemir, Gözde, Aydemir, Emre, Kızıltoprak, Hasan, Yüksel, ErdemÖzülken K., Aydemir G.A., Aydemir E., Kızıltoprak H., Yüksel E.Erdem YÜKSEL, Emre AYDEMİR, Hasan KIZILTOPRAK, Gözde AKSOY AYDEMİR, Kemal ÖZÜLKENOzulken, K, Aydemir, GA, Aydemir, E, Kiziltoprak, H, Yuksel, E2023-05-092023-05-092020-04-102020-05-012020-11-012020.01.01Yüksel, E., Aydemi̇r, M., Kiziltoprak, H., Aydemi̇r, G., Özülken, K. (2020). Comparison of Two Different Accelerated Corneal Cross-linking Procedure Outcomes in Patients with Keratoconus. Balkan Medical Journal, 37(3), 131-1372146-3123https://hdl.handle.net/20.500.12597/15190https://search.trdizin.gov.tr/publication/detail/373727/comparison-of-two-different-accelerated-corneal-cross-linking-procedure-outcomes-in-patients-with-keratoconushttps://hdl.handle.net/20.500.12597/7218Corneal cross-linking treatment is the unique treatment method that can cease the progression of keratoconus disease. Because of the long duration of conventional treatment, accelerated cross-linking treatment methods are being developed.To compare two different accelerated corneal cross-linking protocols in terms of postoperative visual acuity and topographic findings (higher-order aberrations and keratometry values).Retrospective comparative study.Sixty-five eyes of 43 patients (30 men and 13 women) who underwent two different accelerated corneal cross-linking protocols (10 min, 9 mW/cm and 5 min, 18 mW/cm) for progressive keratoconus were retrospectively analyzed. Patients were divided into two groups according to the accelerated corneal cross-linking treatment protocol: group 1 (10 min, 9 mW/cm, 32 eyes of 21 patients) and group 2 (5 min, 18 mW/cm, 33 eyes of 22 patients). Uncorrected visual acuity and best-corrected visual acuity values and topographic findings (central corneal thickness and flat and steep keratometry values) were recorded preoperatively and 6 months after corneal cross-linking treatment. High-order aberration values measured with Pentacam preoperatively and 6 months after corneal cross-linking were also recorded.In both groups, a significant improvement was detected in the uncorrected visual acuity and best-corrected visual acuity levels preoperatively and 6 months postoperatively (group 1: p=0.001, p=0.001 and group 2: p=0.001, p=0.001, respectively). In addition, central corneal thickness values decreased significantly in both groups (p=0.006 and 0.001). Trefoil values showed no significant difference preoperatively and 6 months postoperatively in group 1 (p=0.160 and 0.620, respectively). In groups 1 and 2, coma values were found to decrease significantly in the 6 postoperative month compared with preoperative values (p=0.001 and 0.020, respectively). There was no significant difference between preoperative and 6 month postoperative horizontal and vertical trefoil values in both groups (p=0.850 and 0.140, respectively). There was no significant difference between the two groups in terms of preoperative and 6 month postoperative higher-order aberrations, refractive errors, keratometry values, and uncorrected visual acuity and best-corrected visual acuity levels.Both accelerated corneal cross-linking procedures provide similar improvement in topographic findings, coma values and visual acuity.Background: Corneal cross-linking treatment is the unique treatment method that can cease the progression of keratoconus disease. Because of the long duration of conventional treatment, accelerated cross-linking treatment methods are being developed. Aims: To compare two different accelerated corneal cross-linking protocols in terms of postoperative visual acuity and topographic findings (higher-order aberrations and keratometry values). Study Design: Retrospective comparative study. Methods: Sixty-five eyes of 43 patients (30 men and 13 women) who underwent two different accelerated corneal cross-linking protocols (10 min, 9 mW/cm2 and 5 min, 18 mW/cm2) for progressive keratoconus were retrospectively analyzed. Patients were divided into two groups according to the accelerated corneal cross-linking treatment protocol: group 1 (10 min, 9 mW/cm2, 32 eyes of 21 patients) and group 2 (5 min, 18 mW/cm2, 33 eyes of 22 patients). Uncorrected visual acuity and best-corrected visual acuity values and topographic findings (central corneal thickness and flat and steep keratometry values) were recorded preoperatively and 6 months after corneal cross-linking treatment. High-order aberration values measured with Pentacam preoperatively and 6 months after corneal cross-linking were also recorded. Results: In both groups, a significant improvement was detected in the uncorrected visual acuity and best-corrected visual acuity levels preoperatively and 6 months postoperatively (group 1: p=0.001, p=0.001 and group 2: p=0.001, p=0.001, respectively). In addition, central corneal thickness values decreased significantly in both groups (p=0.006 and 0.001). Trefoil values showed no significant difference preoperatively and 6 months postoperatively in group 1 (p=0.160 and 0.620, respectively). In groups 1 and 2, coma values were found to decrease significantly in the 6th postoperative month compared with preoperative values (p=0.001 and 0.020, respectively). There was no significant difference between preoperative and 6th month postoperative horizontal and vertical trefoil values in both groups (p=0.850 and 0.140, respectively). There was no significant difference between the two groups in terms of preoperative and 6th month postoperative higher-order aberrations, refractive errors, keratometry values, and uncorrected visual acuity and best-corrected visual acuity levels. Conclusion: Both accelerated corneal cross-linking procedures provide similar improvement in topographic findings, coma values and visual acuity.Background: Corneal cross-linking treatment is the unique treatmentmethod that can cease the progression of keratoconus disease.Because of the long duration of conventional treatment, acceleratedcross-linking treatment methods are being developed.Aims: To compare two different accelerated corneal cross-linkingprotocols in terms of postoperative visual acuity and topographicfindings (higher-order aberrations and keratometry values).Study Design: Retrospective comparative study.Methods: Sixty-five eyes of 43 patients (30 men and 13 women)who underwent two different accelerated corneal cross-linkingprotocols (10 min, 9 mW/cm2 and 5 min, 18 mW/cm2) for progressivekeratoconus were retrospectively analyzed. Patients were dividedinto two groups according to the accelerated corneal cross-linkingtreatment protocol: group 1 (10 min, 9 mW/cm2, 32 eyes of 21patients) and group 2 (5 min, 18 mW/cm2, 33 eyes of 22 patients).Uncorrected visual acuity and best-corrected visual acuity values andtopographic findings (central corneal thickness and flat and steepkeratometry values) were recorded preoperatively and 6 monthsafter corneal cross-linking treatment. High-order aberration valuesmeasured with Pentacam preoperatively and 6 months after cornealcross-linking were also recorded.Results: In both groups, a significant improvement was detected inthe uncorrected visual acuity and best-corrected visual acuity levelspreoperatively and 6 months postoperatively (group 1: p=0.001,p=0.001 and group 2: p=0.001, p=0.001, respectively). In addition,central corneal thickness values decreased significantly in both groups(p=0.006 and 0.001). Trefoil values showed no significant differencepreoperatively and 6 months postoperatively in group 1 (p=0.160and 0.620, respectively). In groups 1 and 2, coma values were foundto decrease significantly in the 6th postoperative month comparedwith preoperative values (p=0.001 and 0.020, respectively). Therewas no significant difference between preoperative and 6th monthpostoperative horizontal and vertical trefoil values in both groups(p=0.850 and 0.140, respectively). There was no significant differencebetween the two groups in terms of preoperative and 6th monthpostoperative higher-order aberrations, refractive errors, keratometryvalues, and uncorrected visual acuity and best-corrected visual acuitylevels.Conclusion: Both accelerated corneal cross-linking proceduresprovide similar improvement in topographic findings, coma valuesand visual acuitytrueinfo:eu-repo/semantics/openAccessAccelarated cross-linkingcomacorneal cross-linkincxlhigher-order aberationskeratoconusAccelarated cross-linking | Coma | Corneal cross-linkin | Cxl | Higher-order aberations | KeratoconusJournal Article10.4274/balkanmedj.galenos.2020.2019.8.4510.4274/balkanmedj.galenos.2020.2019.8.452-s2.0-85083620490WOS:00052608210000431909581373727131131137137372146-3131