Inanc M.Kiziltoprak H.Hekimoglu R.Tekin K.Ozalkak S.Koc M.Bayramoglu E.Zirh S.Yuruker S.Aycan Z.2023-04-122023-04-122020-04-0209273948https://hdl.handle.net/20.500.12597/4763Purpose: To investigate whether diabetes mellitus (DM) affects ocular surface of children with well-controlled type 1 DM. Methods: Sixty-five diabetic patients and 55 age-matched controls enrolled to study. Detailed ocular surface assessment including, ocular surface disease index (OSDI) questionnaire, tear film break-up time (TBUT) analysis, Schirmer test, and conjunctival impression cytologic analysis were performed. Results: Schirmer test and TBUT results were significantly lower in DM group than controls (p = 0.001, for all). OSDI scores of all participants were within normal range. Impression cytology analysis showed grade 0 changes in all participants and there was no difference between groups for goblet cell density (p > 0.05). The TBUT results were significantly associated with duration of DM (r = −0.309, p = 0.036). Conclusion: Diabetic children without symptoms, signs, and definite diagnosis of dry eye still had lower TBUT and Schirmer test results than controls; however, impression cytology analysis was similar in both groups.falsedry eye | impression cytology | mellitus | ocular surface | tear filmArticle10.1080/09273948.2019.15712122-s2.0-8506237517530806526