Erbil, G.Ç.Elp, M.Durmaz, Y.2024-07-222024-07-222024.01.012589-014Xhttps://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=dspace_ku&SrcAuth=WosAPI&KeyUT=WOS:001265974600001&DestLinkType=FullRecord&DestApp=WOS_CPLhttps://hdl.handle.net/20.500.12597/33436The study aimed to investigate the possible use of myo-inositol as a carbon source in Chlorella sp. culture. Firstly, experiments were conducted with different myo-inositol concentrations and glycerol in flasks. Secondly, a laboratory-scale tubular photobioreactor (PBR) was operated with CO2 and myo-inositol to determine performance under industrial production conditions. The highest dry weight of the experiments with flasks was 1.62 +/- 0.02 g.L-1 and was obtained with 1 g.L-1 myo-inositol concentration. Myo-inositol yielded two times higher lipid accumulation compared to glycerol in the experiment with flasks and 12 % compared to CO2 in the PBR experiment. The results revealed that myo-inositol is one of the most efficient carbon sources with 0.86 CBCR (carbon to biomass conversion rate). Even if myo-inositol is more expensive than many carbon sources such as CO2, high efficiency and less light energy expenses make it a competitive carbon source in Chlorella sp. production.eninfo:eu-repo/semantics/openAccessFatty acidLipidMicroalgaeMixotrophicMyo-inositolPigmentArticle10.1016/j.biteb.2024.10186100126597460000126