MuĞlu, Halit, Yakan, Hasan, Bakir, Temel KanMuǧlu H., Yakan H., Bakir T.K.Hasan YAKAN, Temel Kan BAKIR, Halit MUĞLUMuglu, H, Yakan, H, Bakir, TK2023-05-092023-05-092020-02-112020-01-012020-02-012020.01.01Yakan, H., Bakir, T., Muğlu, H. (2020). Synthesis, spectroscopic studies, and antioxidant activities of novel thio/carbohydrazones and bis-isatin derivatives from terephthalaldehyde. Turkish Journal of Chemistry, 44(1), 237-2481300-0527https://hdl.handle.net/20.500.12597/15112https://search.trdizin.gov.tr/publication/detail/335157/synthesis-spectroscopic-studies-and-antioxidant-activities-of-novel-thiocarbohydrazones-and-bis-isatin-derivatives-from-terephthalaldehydehttps://hdl.handle.net/20.500.12597/7275New bis(isatins-thio/carbohydrazones) based on Schiff bases were prepared from terephthalaldehyde biscarbohydrazone and 5-substituted isatins in the presence of a drop of sulfuric acid under reflux in ethanol. Terephthalaldehyde bis(thio/carbohydrazone) was synthesized by the reaction of (thio)/carbohydrazide and terephthalaldehyde in the presence of a few drops of acetic acid under reflux in ethanol. The structures of these synthesized compounds were determined using IR, H NMR, and C NMR spectroscopy and elemental analysis. The in vitro antioxidant activity of all the compounds was determined by the 1,1-diphenyl-2-picryl hydrazyl (DPPH.) free radical scavenging method. Compound 2 showed the best antioxidant activity.New bis(isatins-thio/carbohydrazones) based on Schiff bases were prepared from terephthalaldehyde bis-carbohydrazone and 5-substituted isatins in the presence of a drop of sulfuric acid under reflux in ethanol. Terephthalaldehyde bis(thio/carbohydrazone) was synthesized by the reaction of (thio)/carbohydrazide and terephthalaldehyde in the presence of a few drops of acetic acid under reflux in ethanol. The structures of these synthesized compounds were determined using IR, 1H NMR, and 13C NMR spectroscopy and elemental analysis. The in vitro antioxidant activity of all the compounds was determined by the 1,1-diphenyl-2-picryl hydrazyl (DPPH) free radical scavenging method. Compound 2 showed the best antioxidant activity.New bis(isatins-thio/carbohydrazones) based on Schiff bases were prepared from terephthalaldehyde biscarbohydrazone and 5-substituted isatins in the presence of a drop of sulfuric acid under reflux in ethanol. Terephthalaldehyde bis(thio/carbohydrazone) was synthesized by the reaction of (thio)/carbohydrazide and terephthalaldehyde inthe presence of a few drops of acetic acid under reflux in ethanol. The structures of these synthesized compounds weredetermined using IR, 1 H NMR, and 13 C NMR spectroscopy and elemental analysis. The in vitro antioxidant activityof all the compounds was determined by the 1,1-diphenyl-2-picryl hydrazyl (DPPH.) free radical scavenging method.Compound 2 showed the best antioxidant activity.falseinfo:eu-repo/semantics/openAccessDPPHIsatinSchiff basescarbohydrazonespectroscopic techniquesCarbohydrazone | DPPH | Isatin | Schiff bases | Spectroscopic techniquesSynthesis, spectroscopic studies, and antioxidant activities of novel thio/carbohydrazones and bis-isatin derivatives from terephthalaldehyde.Synthesis, spectroscopic studies, and antioxidant activities of novel thio/carbohydrazones and bis-isatin derivatives from terephthalaldehydeSynthesis, spectroscopic studies, and antioxidant activities of novel thio/carbohydrazones and bis-isatin derivatives from terephthalaldehydeSynthesis, spectroscopic studies, and antioxidant activities of novel thio/carbohydrazones and bis-isatin derivatives from terephthalaldehydeJournal Article10.3906/kim-1910-1310.3906/kim-1910-132-s2.0-85081959349WOS:00051377100001833488154335157237237248+44