Browsing by Author "Ugras S."

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Assessing Effectiveness of anaerobic threshold and respiratory compensation point on fat and carbohydrate oxidations during exercise in sedentary males
(2020-12-21) Ugras S.; Algul S.; Ozcelik O.
Study Objectives: Anaerobic threshold (AT) and respiratory compensation point (RCP) are two important metabolic set points. We aimed to determine the effects of exercise intensity at AT and RCP on the balance of substrate oxidation rates. Methods: Eleven male participants performed an incremental exercise test to exhaustion on a cycle ergometer to estimate AT and RCP. Subsequently, we conducted three 30 minute constant load exercise tests at AT (WAT), RCP (WRCP) and 25% below AT (W
Breathing patterns response to the incremental exercise test in young males
(2021-03-01) Ugras S.; Ozcelik O.
Incremental exercise test contains three different metabolic regions, including aerobic region, partly anaerobic and anaerobic dominated region. The work load from warm up period to anaerobic threshold (AT) was accepted as aerobic region, workload above AT to respiratory compensation point (RCP) was accepted partly anaerobic region and above RCP was accepted as anaerobic region of incremental exercise test. We aimed to compare the ventilatory patterns during different metabolic sections of incremental exercise test. Fifteen healthy males performed an incremental exercise test (15 W/min) to exhaustion on a cycle ergometer. Metabolic and cardiopulmonary parameters were measured breath-by-breath using metabolic gas analyser system and turbine volume meter. AT and RCP were estimated using ventilator and pulmonary gas exchange parameters. Respiratory patterns, breathing frequency (Bf) and tidal volume (VT), showed great differences among the exercise regions. VT is the main factor increases minute ventilation (VE) during aerobic region. However, Bf becomes dominant factor increasing VE in anaerobic region of test. In the region between AT to RCP, Bf and VT showed similar effects on increase in VE. VT to inspiratory time ratio increased significantly in all region of test. However, work production capacity for each liter of VE decreased markedly when the exercise intensity changed from aerobic to anaerobic regions. Consequently, evaluation of breathing patterns for different metabolic regions of incremental exercise will provide information regarding individual's metabolic strength and ventilator response.
Investigation of irisin level in brucella patients
(2021-01-01) Algul S.; Senol F.F.; Ugras S.; Esmer F.; Kara M.; Ekici P.; Ozcelik O.
This study aimed to determine whether the changes in the metabolism of Brucella patients affect the irisin hormone. Also, it is aimed to investigate the relationships between other laboratory findings used in the diagnosis of brucellosis patients and the irisin hormone. 160 persons (80 brucellosis, 80 controls) were included in this study. Blood was drawn from the people participating in the study following their overnight fast. Irisin level was measured by ELISA method, CRP and sedimentation levels were measured using autoanalysers and commercial kits. It was determined that the irisin level of Brucella patients was statistically significantly higher than the control group (p <0.05). It was determined that there is a negative correlation between irisin level and CRP and sedimentation level in Brucella patients. In Brucella patients, the higher irisin level than the control group showed a negative correlation with CRP and sedimentation levels, which are infection diagnosis criteria; It suggests that the level of irisin can be considered as a supportive diagnostic marker in these patients. Further studies are needed to evaluate irisin hormone as a supportive diagnostic criterion.